Prevalence of Metabolic Syndrome in Moderate to Severe Chronic Plaque Psoriatic Patients in Phra Nakhon Si Ayutthaya Hospital

Abstract

     Psoriasis is a chronic inflammatory dermatitis found commonly in medical practices. Studies found the psoriasis association with metabolic syndrome which lead to cardiovascular disease. The study aimed to examine the prevalence of metabolic syndrome in moderate to severe chronic plaque psoriatic patients at dermatologic outpatient clinic of Phra Nakhon Si Ayutthaya hospital during June to December 2018. A total of 32 of moderate to severe chronic plaque psoriatic patients (19 males, 59.4% and 13 females, 40.6%), 20 were found with metabolic syndrome (12 males, 8 females). The prevalence of metabolic syndrome was 62.5% with 63.2% for male group and 61.5% for female group. Compared to moderate to severe chronic plaque psoriatic patients with regular metabolic parameters, those with abnormal waist line, blood sugar, blood pressure and triglyceride were diagnosed metabolic syndrome with odds ratio 209, 13.4, 11.7 and 9.3 respectively in statistically significant. Patients with abnormal high-density lipoprotein cholesterol and gender had no significant association with metabolic syndrome.