Efficacy and Safety of Protein Power Drink Products in Volunteers with Sarcopenia
Keywords:
Sarcopenia, Animal-Based Protein, Plant-based protein, Efficacy, SafetyAbstract
Sarcopenia is a condition that negatively affects the quality of life of older adults and increases the risk of various complications. Adequate protein intake is a key approach to managing this condition. However, studies on the effects of animal-based and plant-based protein isolates on muscle performance remain limited. Therefore, this study aimed to evaluate and compare the efficacy and safety of protein powder drink formulated with animal-based whey protein isolate and multi-source plant-based protein isolates in individuals with sarcopenia. This randomized controlled trial was conducted in 33 participants who consumed one serving of the assigned protein powder drink (one sachet mixed with 250 mL of water) once daily for 12 consecutive weeks. Muscle strength, muscle mass, physical performance, blood parameters, and adverse events were evaluated. The results showed that both the animal-based and plant-based protein powder drink groups demonstrated significant improvements in physical performance compared with the control group (p<0.05). No adverse effects were observed in the skin, respiratory, or gastrointestinal systems, and no significant changes were found in liver or kidney function. Therefore, the findings confirm the efficacy and safety of both animal and plant protein isolates powder drink, suggesting that these protein powder drink may serve as alternative options for managing sarcopenia. Plant-based protein may serve as an appropriate alternative for individuals who prefer to avoid animal-derived product.
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