Coffee Consumption Patterns, Metabolic Factors and The Risk of Hypertension Related to Obesity
Keywords:
obesity, coffee consumption, hypertension, metabolic syndromeAbstract
Obesity contributes to risk factors for metabolic syndrome including high cholesterol, insulin resistance, and high blood pressure, which may lead to hypertension, cardiovascular disease, and type 2 diabetes (T2DM). Consequently, dietary strategies have been proposed to manage obesity and its comorbidities. A large number of studies reported that coffee consumption have been associated with both a lower and higher risk of hypertension in people who drink it habitually. This study investigated the relationship between coffee consumption, various metabolic factors, and risk of hypertension among obese men compared to those who were not obese. Participants were 358 men aged 45-60 years. Information related to their characteristics, biochemical parameters, and coffee consumption patterns were analyzed based on body mass index (BMI) and blood pressure (normal, prehypertension, and hypertension grade I/II). Results showed significant correlations between SBP and DBP with BMI, WC, TG, LDL-C, UA, FBG, and HbA1C in obese men with prehypertension and HT grade I/II (all p values < 0.05). Compared to non-coffee drinkers, participants who drank coffee showed significantly higher SBP and DBP. In addition, multinomial logistic regression analysis identified significant factors associated with the risk of prehypertension and hypertension, including uric acid, TG, coffee intake, number of coffees consumed, and the addition of sugar/creamer. Our findings suggest that coffee consumption associated with hypertension and obesity increased with the quantity of coffee consumed over a long period of time, which should be a concern. To better understand the causal relationship between coffee consumption and metabolic syndrome, more longitudinal studies are required.
References
Noncommunicable diseases country profiles 2018. Available online: https://apps.who.int/iris/ handle/10665/274512 (accessed on 28 April 2022)
Ng R, Sutradhar R, Yao Z, Wodchis WP, Rosella LC. Smoking, drinking, diet and physical activity-modifiable lifestyle risk factors and their associations with age to first chronic disease. Int J Epidemiol 2020;49(1):113-130.
Castro-Quezada I, Román-Viñas B, Serra-Majem L. The Mediterranean diet and nutritional adequacy: a review. Nutrients 2014;6(1):231-48.
Shahbandhen M. Global Coffee Consumption 2012/13–2018/19. [(accessed on 20 February 2022)];2020 Jan; Available online: https://www.statista.com/statistics/292595/global-coffee-consumption/#statisticContainer
Polsripradist P, Tantayaporn K, Homchampa P. Caffeine consumption behaviors of the working-age population in rural communities in northeastern Thailand. J Med Assoc Thai 2016;99(7):839-51.
Nuhu AA. Bioactive micronutrients in coffee: recent analytical approaches for characterization and quantification. ISRN Nutr 2014;2014:384230.
Shariq OA, McKenzie TJ. Obesity-related hypertension: a review of pathophysiology, management, and the role of metabolic surgery. Gland Surg 2020;9(1):80-93.
Maki C, Funakoshi-Tago M, Aoyagi R, Ueda F, Kimura M, Kobata K, et al. Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS1. PLoS One 2017;12(3):e0173264.
Lee J, Kim HY, Kim J. Coffee consumption and the risk of obesity in Korean women. Nutrients 2017;9(12):1340.
Jee SH, He J, Whelton PK, Suh I, Klag MJ. The effect of chronic coffee drinking on blood pressure: a meta-analysis of controlled clinical trials. Hypertension1999;33(2):647-52.
Miranda AM, Goulart AC, Benseñor IM, Lotufo PA, Marchioni DM. Coffee consumption and risk of hypertension: A prospective analysis in the cohort study. Clin Nutr 2021;40(2):542-549.
Vathesatogkit P, Woodward M, Tanomsup S, Ratanachaiwong W, Vanavanan S,Sritara P, et al. Cohort Profile: The electricity generating authority of Thailand study. Int J Epidemiol 2012;41(2):359-65.
Svetkey LP. Management of prehypertension. Hypertension 2005 Jun;45(6):1056-61.
Guagnano MT, Ballone E, Colagrande V, Della Vecchia R, Manigrasso MR, Merlitti D, et al. Large waist circumference and risk of hypertension. Int J Obes Relat Metab Disord 2001;25(9):1360-4.
Momin M, Fan F, Li J, Jia J, Zhang L, Zhang Y, et al. Joint effects of body mass index and waist circumference on the incidence of hypertension in a community-based Chinese population. Obes Facts 2020;13(2):245-255.
El Meouchy P, Wahoud M, Allam S, Chedid R, Karam W, Karam S. Hypertension related to obesity: Pathogenesis, characteristics and factors for control. Int J Mol Sci 2022;23(20):12305.
Tang N, Ma J, Tao R, Chen Z, Yang Y, He Q, et al. The effects of the interaction between BMI and dyslipidemia on hypertension in adults. Sci Rep 2022;12(1):927.
Scherrer U, Randin D, Vollenweider P, Vollenweider L, Nicod P. Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest 1994;94:2511–2515.
Horita S, Seki G, Yamada H, Suzuki M, Koike K, Fujita T. Insulin resistance, obesity, hypertension, and renal sodium transport. Int J Hypertens 2011;2011:391762.
Rospleszcz S, Dermyshi D, Müller-Peltzer K, Strauch K, Bamberg F, Peters A. Association of serum uric acid with visceral, subcutaneous and hepatic fat quantified by magnetic resonance imaging. Sci Rep 2020;10(1):442.
Li F, Chen S, Qiu X, Wu J, Tan M, Wang M. Serum uric acid levels and metabolic indices in an obese population: A cross-sectional study. Diabetes Metab Syndr Obes 2021;14:627-635.
Kang D-H, Han L, Ouyang X, Kahn AM, Kanellis J, Li P, et al. Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter. Am J Nephrol 2005;25:425-433.
Sánchez-Lozada LG, Lanaspa MA, Cristóbal-García M, García-Arroyo F, Soto V, Cruz-Robles D, et al. Uric acid-induced endothelial dysfunction is associated with mitochondrial alterations and decreased intracellular ATP concentrations. Nephron Experimental Nephrology 2012, 121:e71-e78.
Hou C, Zeng Y, Chen W, Han X, Yang H, Ying Z, Hu Y, Sun Y, Qu Y, Fang F, Song H. Medical conditions associated with coffee consumption: Disease-trajectory and comorbidity network analyses of a prospective cohort study in UK Biobank. Am J Clin Nutr 2022 Sep 2;116(3):730-740.
Sharma H. A Detail Chemistry of Coffee and Its Analysis [Internet]. Coffee-Production and Research. IntechOpen; 2020. Available from: http://dx.doi.org/10.5772/intechopen.91725
Pan H, Gao Y, Tu Y. Mechanisms of Body Weight Reduction by Black Tea Polyphenols. Molecules 2016 Dec 7;21(12):1659.
Nishitsuji K, Watanabe S, Xiao J, Nagatomo R, Ogawa H, Tsunematsu T, Umemoto H, Morimoto Y, Akatsu H, Inoue K, Tsuneyama K. Effect of coffee or coffee components on gut microbiome and short-chain fatty acids in a mouse model of metabolic syndrome. Sci Rep 2018 Nov 1;8(1):16173.
Klag MJ, Wang NY, Meoni LA, Brancati FL, Cooper LA, Liang KY, et al. Coffee intake and risk of hypertension: the Johns Hopkins precursors study. Arch Intern Med 2002;162(6):657-62.
Palatini P, Dorigatti F, Santonastaso M, Cozzio S, Biasion T, Garavelli G, et al. Association between coffee consumption and risk of hypertension. Ann Med 2007;39(7):545-53.
Surma S, Oparil S. Coffee and arterial hypertension. Curr Hypertens Rep 2021;23(7):38.
Cruchten ST, de Waart DR, Kunne C, Hooiveld GJ, Boekschoten MV, Katan MB, et al. Absorption, distribution, and biliary excretion of cafestol, a potent cholesterol-elevating compound in unfiltered coffees, in mice. Drug Metab Dispos 2010;38(4):635-40.
van Tol A, Urgert R, de Jong-Caesar R, van Gent T, Scheek LM, de Roos B, et al. The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans. Atherosclerosis 1997;132(2):251-4.
Creager MA, Cooke JP, Mendelsohn ME, Gallagher SJ, Coleman SM, Loscalzo J, Dzau VJ. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. J Clin Invest 1990;86:228–234.
Downloads
Published
How to Cite
Issue
Section
License
Upon acceptance of an article, copyright is belonging to the Nutrition Association of Thailand.
