Effects of Pandanus Amaryllifolius Leaf Beverage on Postprandial Blood Glucose and Satiety Level in Thai Healthy Volunteers
Keywords:Pandanus Amaryllifolius, Blood glucose, Satiety
Pandanus Amaryllifolius (PA) leaf extracts were associated with reducing blood glucose levels in animal models; however, the effects of PA leaf beverages on blood glucose in humans are required to clarify this association. This study evaluated the effect of PA leaf beverage consumption on postprandial blood glucose, satiety level and metabolic responses in Thai healthy volunteers. This was a randomized crossover study. Thirteen healthy volunteers aged between 20 and 23 years old were randomly assigned to consume either glucose solution (25 g of glucose powder in 150 ml of water) or PA beverage (2 g of PA dried leaf powder plus 25 g of glucose powder in 150 ml of water). Blood glucose, satiety, blood pressure, heart rate, and body temperature were measured at baseline (0 minute) and at 30-, 60-, 90-, and 120 minutes after consuming the beverages. Postprandial blood glucose level after consuming PA beverage was 10% significantly higher than those of glucose solution at 90 min (p<0.05). However, the area under the curve (AUC 0-90) of postprandial blood glucose when consumed PA beverage was slightly smaller than when consuming glucose solution (178.50 ± 20.34 and 180.21 ± 16.21, respectively). Moreover, satiety levels at 30, 60, 90, and 120 minutes after consuming PA beverage were higher, but not significant, than when consumed glucose only. There were no differences in blood pressure, heart rate, and body temperature comparing the consumption of the two beverages. This study suggested that a single dose of 2 g of PA with 25 g glucose did not improve blood glucose regulation. There was no statistical difference in satiety score between PA and control group.
รายงานสถานการณ์โรค NCDs พ.ศ. 2562 เบาหวาน ความดันโลหิตสูง และปัจจัยเสี่ยงที่เกี่ยวข้อง. กรมควบคุมโรค กองโรคไม่ติดต่อ กระทรวงสาธารณสุข [เข้าถึงเมื่อ 18 เมษายน 2566]. เข้าถึงได้จาก: https://ddc.moph.go.th/uploads/publish/1035820201005073556.pdf
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