ผลวิเคราะห์สารประกอบฟีนอลิกรวมและสารประกอบฟลาโวนอยด์ของสมุนไพรจีน:  ชังจู๋ ไป๋จู๋ และ หวงเหลียน

Sucha Chulsomlee; Chompunoot Sinthupibulyakit; Penpak Moolthiya; Nontawit Pirat; Kanjana Vichittumaros; Napassanun Narasinviwat; Jirawat Pratoomwun; Nonthaya Thangrua

Authors

Sucha Chulsomlee Faculty of Medical Technology, Huachiew Chalermprakiet University
Chompunoot Sinthupibulyakit Faculty of Medical Technology, Huachiew Chalermprakiet University
Penpak Moolthiya Faculty of Medical Technology, Huachiew Chalermprakiet University
Nontawit Pirat Faculty of Medical Technology, Huachiew Chalermprakiet University
Kanjana Vichittumaros Faculty of Medical Technology, Huachiew Chalermprakiet University
Napassanun Narasinviwat Faculty of Pharmaceutical Sciences, Huachiew Chalermprakiet University
Jirawat Pratoomwun Faculty of Medical Technology, Huachiew Chalermprakiet University
Nonthaya Thangrua Faculty of Medical Technology, Huachiew Chalermprakiet University

Keywords:

Total phenolic compound, flavonoid, Atractylodes lancea (Thunb.) DC., Atractylodes macrocephala Koidz, Coptis chinensis Franch

Abstract

The primary objective of this research was to quantify the total phenolic and flavonoid compounds in three types of Chinese herb extracts using the Folin-Ciocalteu method and the Aluminum Nitrate colorimetric method, respectively. The herbs analyzed were Atractylodes lancea (Thunb.) DC., Atractylodes macrocephala Koidz, and Coptis chinensis Franch, all extracted with 95% methanol. These herbs are components of traditional Chinese medicine recipes used for the treatment of stomach and spleen disorders. The study found that the total phenolic compounds in Atractylodes lancea (Thunb.) DC., Atractylodes macrocephala Koidz, and Coptis chinensis Franch were 1.95±0.48, 3.40±0.74, and 12.18±2.15 mg GAE/g, respectively. The flavonoid compounds in Atractylodes lancea (Thunb.) DC., Atractylodes macrocephala Koidz, and Coptis chinensis Franch were 8.45±1.25, 9.05±0.56, and 15.24±1.77 mg QE/g, respectively. The results indicated that Coptis chinensis Franch extract showed the highest levels of total phenolic and flavonoid compounds, while Atractylodes lancea (Thunb.) DC. extract showed the lowest. Statistically significant differences (p < 0.05) were found between Coptis chinensis Franch and both Atractylodes lancea (Thunb.) DC. and Atractylodes macrocephala Koidz in terms of both total phenolic and flavonoid compounds. To develop herbal extracts for medicinal use, further studies are needed on the mechanisms of action and the safety of using these herbal medicines in both in-vitro and in animal trials.

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