Acute Effects of Dynamic Handgrip Exercise on Cardio Ankle Vascular Index in Diabetes Patient

Authors

  • Pott Pongpaopattanakul Department of Cardio-Thoracic Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand 65000
  • Thamonwan Imerbtham Department of Cardio-Thoracic Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand 65000
  • Nanthawat Buphasiri Department of Cardio-Thoracic Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand 65000
  • Surarak Sangmanee Department of Cardio-Thoracic Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand 65000
  • Pijittra Puangkhum Department of Cardio-Thoracic Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand 65000

Keywords:

Arterial stiffness, cardio ankle vascular index, diabetes mellitus, dynamic handgrip exercise

Abstract

Increase arterial stiffness is associated with increased risk of coronary artery disease (CAD) and stroke. This clinical parameter could be measured by a cardio ankle vascular index (CAVI). Many exercise techniques, include aerobic and isometric handgrip exercises, have been studied to improve vascular function in vascular disease patients, which showed increase arterial stiffness during acute response, since data of dynamic handgrip exercise (DHE) effect in diabetes mellitus (DM) patients is limited. This study aims to investigate acute CAVI response to DHE in DM patients. 14 DM type 2 and 14 healthy participants were enrolled. Hemodynamics and CAVI were evaluated at rest and immediately after 3 minutes DHE. At rest, DM patients were higher in right and left CAVIs than the control. DHE significantly increased heart rate (HR), systolic blood pressure (SBP), and CAVI parameters of the DM group. The DM group exhibited larger increases of R CAVI (control vs. DM: 0.39 ± 0.48 vs. 0.78 ± 0.72, P = 0.102) and L CAVI (control vs. DM: 0.24 ± 0.50 vs. 0.78 ± 0.68, P = 0.025) post DHE. Change of time between rise of left brachial pulse wave and rise of left ankle pulse wave (ΔL tba) was greater in DM (control vs. DM: -2.64 ± 2.76 ms vs. -5.43 ± 3.84 ms, P = 0.037). DHE produced increases in HR, SBP, and CAVI as acute responses with larger CAVI changes observed in DM. This arterial stiffness response was similar to acute results by aerobic and isometric exercises.

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References

Vatner SF, Zhang J, Vyzas C, Mishra K, Graham RM, Vatner DE. Vascular stiffness in aging and disease. Front Physiol 2021;12:762437.

Miyoshi T, Ito H, Shirai K, Horinaka S, Higaki J, Yamamura S, et al. Predictive Value of the Cardio-Ankle Vascular Index for Cardiovascular Events in Patients at Cardiovascular Risk. J Am Heart Assoc 2021;10(16):e020103.

Namba T, Masaki N, Takase B, Adachi T. Arterial stiffness assessed by cardio-ankle vascular index. Int J Mol Sci 2019;20(15):3664.

Kollet DP, Marenco AB, Bellé NL, Barbosa E, Boll L, Eibel B, et al. Aerobic exercise, but not isometric handgrip exercise, improves endothelial function and arterial stiffness in patients with myocardial infarction undergoing coronary intervention: a randomized pilot study. BMC Cardiovasc Disord 2021;21(1):101.

Correia MA, Oliveira PL, Farah BQ, Vianna LC, Wolosker N, Puech‐Leao P, et al. Effects of isometric handgrip training in patients with peripheral artery disease: a randomized controlled trial. J Am Heart Assoc 2020;9(4):e013596.

Moon S-H, Moon J-C, Heo D-H, Lim Y-H, Choi J-H, Kim S-Y, et al. Increased pulse wave velocity and augmentation index after isometric handgrip exercise in patients with coronary artery disease. Clin Hypertens 2015;21(1):5.

Hartog R, Bolignano D, Sijbrands E, Pucci G, Mattace-Raso F. Short-term vascular hemodynamic responses to isometric exercise in young adults and in the elderly. Clin Interv Aging 2018;13:509-14.

Cooke AB, Dasgupta K, Spronck B, Sharman JE, Daskalopoulou SS. Adults with type 2 diabetes mellitus exhibit a greater exercise-induced increase in arterial stiffness and vessel hemodynamics. Hypertension 2020;75(6):1565-73.

Pongpaopattanakul P, Imerbtham T, Kitimala J, Phatthanawayu S, Kaewkong P. Effects of a dynamic handgrip exercise on left ventricular diastolic functions in diabetes mellitus patients: A preliminary clinical data. Chula Med J 2022;66(3):283-91.

Samuel TJ, Beaudry R, Haykowsky MJ, Sarma S, Nelson MD. Diastolic stress testing: similarities and differences between isometric handgrip and cycle echocardiography. J Appl Physiol (1985) 2018;125(2):529-35.

Garg R, Malhotra V, Kumar A, Dhar U, Tripathi Y. Effect of isometric handgrip exercise training on resting blood pressure in normal healthy adults. J Clin Diagn Res 2014;8(9):Bc08-10.

Stock JM, Chouramanis NV, Chirinos JA, Edwards DG. Dynamic and isometric handgrip exercise increases wave reflection in healthy young adults. J Appl Physiol 2020;129(4):709-17.

Chirinos JA, Segers P, Raina A, Saif H, Swillens A, Gupta AK, et al. Arterial pulsatile hemodynamic load induced by isometric exercise strongly predicts left ventricular mass in hypertension. Am J Physiol Heart Circ Physiol 2010;298(2):H320-H30.

Schultz MG, Davies JE, Roberts-Thomson P, Black JA, Hughes AD, Sharman JE. Exercise central (aortic) blood pressure is predominantly driven by forward traveling waves, not wave reflection. Hypertension 2013;62(1):175-82.

Li Y, Gu H, Fok H, Alastruey J, Chowienczyk P. Forward and backward pressure waveform morphology in hypertension. Hypertension 2017;69(2):375-81.

Roberto S, Crisafulli A. Consequences of type 1 and 2 diabetes mellitus on the cardiovascular regulation during exercise: a brief review. Curr Diabetes Rev 2017;13(6):560-5.

Staessen JA, van der Heijden-Spek JJ, Safar ME, Den Hond E, Gasowski J, Fagard RH, et al. Menopause and the characteristics of the large arteries in a population study. J Hum Hypertens 2001;15(8):511-8.

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Published

2022-12-23

How to Cite

1.
Pongpaopattanakul P, Imerbtham T, Buphasiri N, Sangmanee S, Puangkhum P. Acute Effects of Dynamic Handgrip Exercise on Cardio Ankle Vascular Index in Diabetes Patient. Journal of Health Sciences and Wellness [Internet]. 2022 Dec. 23 [cited 2024 Nov. 8];26(2):289-9. Available from: https://he01.tci-thaijo.org/index.php/HCUJOURNAL/article/view/256272

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Research article