Risk factors which increase hearing loss in patients with Streptococcus suis infection in Uttaradit hospital
Keywords:
Streptococcus suis, Hearing loss, Risk factorAbstract
The purpose of this research was to study risk factors that increase hearing loss in a patient with Streptococcus suis infection in Uttaradit hospital in Thailand as Streptococcus suis infection inclines to increase constantly particularly in Uttaradit province which has been ranked as the second place in the country and high risk of hearing loss. A retrospective case-control study was designed and data was taken from medical records and audiograms of the patients who visited Uttaradit hospital from 1 January 2009 to 31 October 2019. They were first diagnosed with Streptococcus suis infection and had the evidence of auditory evaluation. Ninety-two patients were chosen which were divided into 38 patients who had sensorineural hearing loss or mixed hearing loss as a study group and another 54 patients who the individual had no hearing loss or conductive hearing loss as a control group. The data of this research were studied using descriptive and analytical statistics. Results and Discussion: The results revealed that dyslipidemia and meningitis were associated with significantly increasing the chance of hearing loss by 28.7 (95%CI=1.20-685.18, p=0.038) and 8.2 (95%CI=1.99-14.19, p=0.004) times, respectively. In patients with hypertension, male and kidney diseases have significantly increased by 2.1 ((95%CI=0.59-7.80, p=0.250), 1.8 (95%CI=0.38-8.68, p=0.457) and 1.4 (95%CI=0.30-6.21, p=0.684)) times, respectively. The descriptive statistics were analyzed using the count data and percentage, the chi-square test and Fisher’s exact test. The univariate and multivariate logistic regression model were used to analyze all explanatory variables interpreted as Odds ratio, 95% CI and p-value. Conclusions: The patients with Streptococcus suis infection and dyslipidemia and/or meningitis have increased the risk of hearing loss. Therefore, the surveillance of these patients is strongly recommended in order to decrease the incidence of hearing loss.
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