Trend of multidrug-resistant organisms (MDROs) Isolated from Clinical Specimens of Patients Admitted to Priest Hospital during 2018-2022
Keywords:
Multidrug-resistant pathogens, Acinetobacter baumannii (CRAB), Pseudomonas aeruginosa (CRPsA), Staphylococcus aureus (MRSA), Enterobacteriaceae (CRE), antimicrobial susceptibility testAbstract
Introduction: The spread of hospital-acquired multidrug resistant organisms (MDROs), including Carbapenem–resistant Acinetobacter baumannii (CRAB), Carbapenem -resistant Pseudomonas aeruginosa (CRPsA), Carbapenem–resistant Enterobacteriaceae (CRE) (Klebsiella pneumoniae and Escherichia coli), and Methicillin–resistant Staphylococcus. aureus (MRSA), is a major problem
directly affecting patients, healthcare professionals and hospitals.
Objective: To study a five-year data trend of MDROs isolated from specimens of patients admitted to Priest Hospital in Bangkok, Thailand.
Methodology: Microbial culture and antimicrobial susceptibility test results were retrieved from the record files managed by the Clinical Microbiology Laboratory under the Division of Pathology at Priest Hospital. The records were dated from the 1st of January, 2018, to the 31st of December, 2022. All data were analyzed with descriptive statistics and presented as tables and graphs.
Results: CRAB was the most abundant type of all the 304 MDRO isolates, accounting for 114 isolates (37.5%). CRAB was found to be most prevalent in patients admitted to the Intensive Care Unit (ICU), with high percentages of CRAB commonly isolated from sputum and pus specimens.
Conclusion: MDROs belonging to the major causes of infection with antimicrobial-resistant agents in patients admitted to The Priest Hospital were CRAB, CRPsA, CRE-K. pneumoniae, MRSA and CRE- E. coli, respectively. The most abundant antimicrobial-resistant organisms was found in pus, sputum, urine and blood specimens, respectively.
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