Treatment Effects and Adverse Drug Reaction of Metta - Osot Cannabis Oil From Medical Records in End Stage Cancer Patients Received Treatment at a Cannabis Clinic, Thai Traditional and Integrated Medicine Hospital, Bangkok

Abstract

This study aimed to investigate the therapeutic effects, adverse reactions, and quality of life of patients with end-stage cancer who were treated with Metta-osot cannabis oil. The data was obtained from medical records at a cannabis clinic. The study used retrospective data from medical records. There were 274 people who received Metta-Osot cannabis oil, but only 147 were collected between August 31, 2020 and January 30, 2023, including both males and females aged 20 to 90.  We collected data from the quality of life questionnaire (EQ - 5D - 5L, ESAS), as well as from records of adverse drug reactions. All relevant data has been gathered. The researcher performed the coding of the data recording form. We converted the acquired data into numerical values and utilized statistical methods to investigate the impact of treatments on the quality of life. We conducted a statistical study to compare the means of a single sample group with repeated measurements. More precisely, we conducted a statistical analysis by comparing the average quality of life at each subsequent visit to the average quality of life at the initial follow-up visit. This comparison was done using a Paired t-test. Additionally, we also examined the occurrence of adverse drug reactions. The research findings indicated that the use of Metta osot cannabis oil can enhance the overall well-being of patients with terminal cancer. It significantly relieves symptoms related to insomnia, loss of appetite, fatigue, physical or mental distress as well as nausea and vomiting. There was a 9 percent occurrence of adverse reactions. Based on the findings of this study, it will be determined that cannabis-containing medications should only be used for medical purposes and under the supervision of a physician or practitioner of Thai traditional medicine. This study has the potential to enhance the scope of clinical research.