A study on the treatment effects and adverse drug reaction of Metta-osot cannabis oil from medical records in end stage cancer patients received treatment at cannabis clinic. Thai Traditional and Integrated Medicine Hospital ,Bangkok

Abstract

      This research was conducted for study the treatment effects, adverse reactions and compare the quality of life of patients who received Metta-osot cannabis oil from medical record in end stage cancer at cannabis clinic. The objective of this study was to promote the proper use of cannabis oil. The research method was to collect retrospective data from medical records. There were 274 people received Metta-Osot cannabis oil between August 31 , 2020 – January 30, 2023 , both males and females aged 20-90 years. We collected information from The quality of life data records (EQ - 5D - 5L, ESAS) and adverse drug reaction data records.

       The results showed that insomnia, loss of appetite, tiredness/fatigue, sick body/mind nausea and vomiting was significantly improved. Adverse drug reactions were reported in 10 patients (9 %). The most common adverse reaction was dizziness. Therefore, it could be concluded that Metta-Osot cannabis oil would be useful in improving the quality of life for cancer patients in long-term palliative stage and it was safe to some extent. There were limitations in data collection from retrospective research. Therefore, this research may need to be extended for clinical practice in order to increase the credibility of further research.