Effects of a cognitive-enhancement group training program for a person with normal cognitive function
Keywords:
cognitive stimulation program, elderly, normal cognitive functionAbstract
This quasi-experimental research, two-group pre-posttest design to evaluate the effects of a cognitiveenhancement group training program for a person with normal cognitive function. The study aimed to compare cognitive performance scores between the experimental and control groups at baseline (pre-test) and following the experiment (post-test) over six months. The sample comprised individuals aged 50 years and older (with an emphasis on those aged 60 years and older) from nine areas within the comprehensive dementia care network. Participants were required to have normal cognitive function as assessed by the MoCA test, be free of anxiety and depression as assessed by the Thai Hospital Anxiety and Depression Scale (Thai HADS), and voluntarily participate in the research. Those who failed to complete all five program sessions or withdrew at any stage were excluded from the study.
A sample of 600 participants was selected via simple random sampling from nine study areas, comprising 313 in the experimental group (52.2%) and 287 in the control group (47.8%). Research instruments included a demographic questionnaire, the Thai HADS, the MoCA, and the ADAS-modified: Thai version. The intervention program, designed to enhance cognitive capacity, consisted of five modules, targeting specific cognitive domains. Each module incorporated three core components: movement-based activities, cognitive stimulation exercises, and follow-up tasks. The program was delivered in five biweekly sessions, each lasting two hours. Data were analyzed using Independent Samples T-test to compare mean scores between the experimental group and the control group, and paired t-test to compare mean scores within the experimental and control groups.
Results showed that the program led to a short-term reduction in anxiety and depressive symptoms in the experimental group. Cognitive performance tests using the MoCA test did not show a significant difference between the experimental and control groups (p > 0.05), suggesting the program may not have an effect on global cognitive function within the six-month timeframe. The ADAS-modified: Thai version indicated a significant decrease in word recall scores in the experimental group (p = 0.002), whereas the control group exhibited a slight increase (p = 0.037). In terms of executive function, the experimental group demonstrated significant improvement (p = 0.001), indicating a positive program effect. Conversely, the control group showed a significant decline in attention scores (p < 0.001), potentially reflecting cognitive decline in the absence of intervention.
While the study results may not yet provide conclusive effect on maintaining cognitive function over the six months, the findings suggested potential benefits of the program in specific cognitive domains. Future research should extend the follow-up period to one to two years to assess the long-term effects of the program on cognitive function.
References
World Health Organization. Dementia [Internet]. Geneva: World Health Organization; 2023 [cited 2024 Mar 15]. Available from: https://www.who.int/news-room/factsheets/detail/dementia
Rojanudomsat A, Kiewkhajee J, Tantirittisak T, editors. Guidelines for the management of dementia (complete edition 2020). Nonthaburi: Neurology Institute, Ministry of Public Health; 2021. (in Thai)
World Health Organization. Global action plan on the public health response to dementia 2017-2025 [Internet]. Geneva: World Health Organization; 2017 [cited 2024 Nov 30]. Available from: https://www.who.int/publications-detail-redirect/global-actionplan-on-the-public-health-response-to-dementia-2017-2025
Alzheimer’s Disease International. Numbers of people with dementia worldwide: an update to the estimates in the World Alzheimer Report 2015 [Internet]. London: Alzheimer’s Disease International; 2020 [cited 2024 Nov 30]. Available from: https://www.alzint.org/about/
World Health Organization. Dementia [Internet]. Geneva: World Health Organization; 2024 [cited 2025 May 8]. Available from: https://www.who.int/news-room/factsheets/detail/dementia
National Statistical Office. The 2021 survey of the older persons in Thailand [Internet]. Bangkok: National Statistical Office; 2022 [cited 2024 May 8]. Available from: https://www.nso.go.th/nsoweb/index (in Thai)
Prasatkul P, editor. The situation of older persons in Thailand 2021. Bangkok: Amarin Printing and Publishing Public Co., Ltd.; 2022. (in Thai)
World Health Organization. Dementia [Internet]. Geneva: World Health Organization; 2019 [cited 2024 Nov 30]. Available from: https://www.who.int/news-room/factsheets/detail/dementia
Mayo Clinic. Alzheimer's stages [Internet]. Rochester (MN): Mayo Foundation for Medical Education and Research; c1998-2020 [updated 2019 Apr 19; cited 2019 Sep 9]. Available from: https://www.mayoclinic.org/diseases-conditions/alzheimersdisease/indepth/alzheimers-stages/art20048448
World Health Organization. Dementia [Internet]. Geneva: World Health Organization; 2024 [cited 2024 Dec 22]. Available from: https://www.who.int/healthtopics/dementia#tab=tab_1
Institute of Geriatric Medicine, Department of Medical Services. Group-based multidimensional cognitive stimulation programs for elderly people with normal cognitive functions [Internet]. Bangkok: Department of Medical Services; 2024 [cited 2024 Nov 30]. Available from: http://agingthai.dms.go.th/agingthai/wpcontent/uploads/2024/12/11122567_001.pdf (in Thai)
Hulley SB, Cummings SR, Browner WS, Grady DG, Newman TB. Designing clinical research. 4th ed. Philadelphia: Wolters Kluwer Health; 2013.
Polit DF, Beck CT. Nursing research: generating and assessing evidence for nursing practice. 11th ed. Philadelphia: Wolters Kluwer; 2021.
Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983;67(6):361-70.
Jobsubin J. Prevalence of anxiety and depression and related factors in breast cancer patients receiving chemotherapy at King Chulalongkorn Memorial Hospital [master's thesis]. Bangkok: Chulalongkorn University; 2020 [cited 2024 Dec 7]. Available from: https://www.car.chula.ac.th
Hemrungrojn S, Tangwongchai S, Charoenboon T, Panasawat M, Supasitthumrong T, Chaipresertsud P, et al. Use of the Montreal cognitive assessment Thai version to discriminate amnestic mild cognitive impairment from Alzheimer's disease and healthy controls: machine learning results. Dement Geriatr Cogn Disord 2021;50(2):183-94
Daochompu D, Kongsakol R, Suksatan W. The effect of cognitive stimulation programs on executive function in individuals with early cognitive impairment. J Psychiatr Assoc Thailand 2020;65(4):345-56. (in Thai)
Chupanya P, Kosiyaporn H. The modified version of the Alzheimer's disease assessment scale (ADAS) in Thai population. J Med Assoc Thai 2013;96(10):1-7. (in Thai)
Jittrapirom P, Chentanez S. The validation of the Thai version of the ADAS-cog for the diagnosis of Alzheimer's disease. J Geriatr Psychiatry Neurol 2015;28(4):255-60
IBM Corp. IBM SPSS Statistics for Windows [software]. Version 28.0. Armonk (NY): IBM Corp; 2021.
Belleville S, Fouquet C, Hudon C, Gagnon JF, Greenwood C, Tsolaki M, et al. Trainingrelated brain plasticity in subjects at risk of developing Alzheimer's disease. Brain 2011;134(6):1623-34. doi: 10.1093/brain/awr068.
Park S, Choi S, Kim J, Kim JY, Heo JH. The effect of cognitive programs on cognitive functions of the elderly with normal cognitive functions in the community: based on the program 'Connect Memories'. J Korean Neurol Assoc 2023;41(1):11-7. doi: 10.17340/jkna.2023.1.2.
Wongjan J, Leethong-In M, Piyawattanapon S. Impact of brain exercise programme on older adults' cognition. J Thai Nurse Midwife Counc [Internet] 2020 [cited 2024 Dec 11];35(2):70-84. Available from: https://he02.tci-thaijo.org/index.php/TJONC/article/view/202323 (in Thai)
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