Reduction of time to access emergency drugs in in-patients with anaphylaxis

Abstract

     Anaphylaxis: “a condition resulting in serious events, life-threatening generalized or systemic hypersensitivity reaction that cause rapidly onset and death in patients”. Moreover, anaphylaxis event is a medical emergency that requires rapid identification and treatment especially access to properly emergency drugs.

Objective: To compare of time in accessing to emergency drug between using Standard emergency box and Super emergency box and the incidence of complications among patients with anaphylaxis.

Method: The retrospective interrupted time analysis research by collecting data from electronic medical recorded programs at Nakornping Hospital was done. In-patients with diagnosis of anaphylaxis during 1 October 2016 to 30 September 2020 were included and divided by using Standard emergency box or Super emergency box.

Result: Forty-four patients received the drug from a Standard emergency box, male (n=22;50%), mean age 37.62 years (SD 25.22), 4 patients (9%) had complication events, 25 % of grade I severity (death) and 25 % of grade H severity (CPR). Five patients had accessed to a Super emergency box, male (n=2, 40%) mean age 46.6 years (SD 16.92), one patient (20%) experienced with complication event in grade H (CPR) severity.

According to the study, after the use of “Super Emergency Box” innovation can reduce waiting time from pharmacy dispensary to patients 71.33 minutes (95%CI: [43.70,98.98], p-value < 0.001) and reduce time in the doctor's diagnosis procedure until the patient receives the full medication according to the treatment plan 80.68 minute (95%CI: [1.39,160.0], p-value = 0.046). The incidence of anaphylaxis complications was not different. (adj OR = 1.17 : 95%CI [0.07-20.04], p-value = 0.912 ).

Conclusion: Super emergency box innovation can reduce the time of emergency drugs access in patients with anaphylaxis and tend to reduce the incidence of complications from anaphylaxis.