Nucleic acid amplification test (NAT) screening for Human Immunodeficiency Virus-1, Hepatitis C Virus and Hepatitis B Vivus of blood donation at The Regional Blood Centre 9, Phisanulok Provinc

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เยาวลักษณ์ วิปสูงเนิน
Uraiwan Boonjan
Worasuntaree Saranrom
Surachedt Onseng
Nuantitha Chaiyasit
Sineenart Oota

Abstract

The National Blood Service Region 9, Phitsanulok screened blood donors by nucleic acid amplification test (NAT), including six samples to detect HIV-1, HCV and HB. At present it has produced synthetic blood but it has various features. There is no substitute for human blood since it is a synthetic non-biodegradable matrix


metabolic process of the body ooze. Screening blood donations are made with NAT blood safety to recipients by meeting the standards of the World Health Organization. The purpose of this study was to study the rate of detection of HIV-1, HCV and HBV testing with NAT (NAT yield rate) to reduce the risk of infection, four from the blood and makes blood more secure level. The patients were studied for the benefit of NAT testing on samples of blood specimens donated to the National Blood Service Region 9, Phitsanulok. The NAT Phitsanulok introduced into used in February 2554 and a sample study to September 2556, if an example by the way Serologic test results were negative, it would confirmed with NAT testing included six samples (minipool 6). Based on blood samples NAT, 119,335 samples (representing 39.1 % of blood donors who tested NAT at the National Blood Service at 9 Phitsanulok) The test results Serologic was a negative total of 115,654 samples. The experiment with how NAT cannot detect HIV RNA, detected HCV RNA of one or HCV NAT yield rate 1:50,237 detectable HBV number 84 or HBV NAT yield rate 1: 1,377 which was consistent with the prevalence of HBV and HCV in Northern. The result demonstrated that the technique used in conjunction with NAT testing methods Serologic in the selection of blood donors it was necessary and useful to enhance the safety of blood and blood components to donate to their patients.

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How to Cite
วิปสูงเนิน เ. ., Boonjan , U. ., Saranrom, W. ., Onseng, S. ., Chaiyasit, N. ., & Oota, S. . (2016). Nucleic acid amplification test (NAT) screening for Human Immunodeficiency Virus-1, Hepatitis C Virus and Hepatitis B Vivus of blood donation at The Regional Blood Centre 9, Phisanulok Provinc. Journal of Disease Prevention and Control : DPC. 2 Phitsanulok, 4(1), 1. retrieved from https://he01.tci-thaijo.org/index.php/dpcphs/article/view/251981
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