Helicobacter pylori antibody and antinuclear antibody in chronic urticaria patients

Abstract

Helicobacter pylori antibody and antinuclear antibody (ANA) were investigated in 138 cases of chronic urticaria patients and 96 normal controls. No statistically significant difference of ANA was shown when comparing between the two groups. The prevalence of positive Helicobacter pylori antibody in chronic urticaria was found to be 45.6 % and 21.9 % in normal subjects (p ≤ 0.001). Positive Helicobacter pylori antibody of 37.3 %, 47.6 % and 59.1 % in chronic urticaria patients were detected in the age range of 15-30 years, 31-45 years and 46-60 years respectively. Helicobacter pylori antibody were presented in 14.3 %, 17.5 % and 35.7 % of normal subjects the age range of 15-30 years, 31-45 years and 46-60 years respectively (p = 0.032, 0.002, 0.100). The prevalence of positive Helicobacter pylori antibody in chronic urticaria patients were found to be 2.61, 2.72 and 1.66 times in the age ranges of 15-30 years, 31-45 years and 46-60 years respectively when comparing with positive result in normal subjects.