Factors associated with multidrug-resistant Pseudomonas aeruginosa infection: a hospital-based case-control study

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Published: Aug 15, 2021
Keywords:
Multidrug resistance Pseudomonas aeruginosa Mechanical ventilator Endotracheal tube

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Peechanika Chopjitt
Faculty of Public Health, Kasetsart University Chalermphrakiat, Sakon Nakhon Campus, Sakon Nakhon, Thailand.
Nuntiput Putthanachote
Department of Clinical Microbiology , Roi Et Hospital, Roi Et, Thailand.
Narongchai Sangsa
Department of Medicine, Roi Et Hospital, Roi Et, Thailand.
Phatsaraporn Sirisa
Department of Infectious Control, Roi Et Hospital, Roi Et, Thailand.
Sermchart Chinnakarnsawas
Department of Medicine, Roi Et Hospital, Roi Et, Thailand.
Chakrit Kankang
Research office, Roi Et Hospital, Roi Et, Thailand.
Benjawan Comhangpol
Department of Infectious Control, Roi Et Hospital, Roi Et, Thailand.
Pakinee Lengwehasatit
Department of Pharmaceutical, Roi Et Hospital, Roi Et, Thailand.
Pisacha Kasemsup
Department of Pharmaceutical, Roi Et Hospital, Roi Et, Thailand.
Wongklang Gudwongsa
Laobuaban Health Promoting Hospital, Mahasarakham, Thailand.
Pongdech Sarakarn
Department of Epidemiology and Biostatistics Faculty of Public Health, Khon Kaen University , Khon Kaen, Thailand.

Abstract

This study aimed to investigate the factors associated with multidrugresistant Pseudomonas aeruginosa (MDR-PA) infection. The study was a hospital-based case-control study. Data were collected from medical records of patients with MDR-PA infection (110 cases) and without MDR-PA infection (110 controls) at the Roi Et Hospital between January 1, 2015 and December 31, 2017. Data analysis used statistics, univariable analysis, and multiple logistic regressions. Statistical significance was set at p-value < 0.05. Most of the 110 cases with MDR-PA infection were male (51.82%) and the mean age was 61.82 ± 15.67 years, while most of the 110 controls were male (56.36%) and the mean age was 55.01 ± 16.09 years. The multivariable analysis revealed that patients aged over 60 years (ORAdj = 2.06, 95%CI = 1.14-3.71), admitted for more than 7 days (ORAdj = 2.43, 95%CI = 1.28-4.60), underwent procedures involving an endotracheal tube (ORAdj = 2.61, 95%CI = 1.42-4.80) and a mechanical ventilator (ORAdj = 3.14, 95%CI = 1.67-5.88). Therefore, the risk factors for MDR-PA infection were patients who were admitted for more than 7 days, who underwent procedures involving an endotracheal tube and a mechanical ventilator.

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1.
Chopjitt P, Putthanachote N, Sangsa N, Sirisa P, Chinnakarnsawas S, Kankang C, Comhangpol B, Lengwehasatit P, Kasemsup P, Gudwongsa W, Sarakarn P. Factors associated with multidrug-resistant Pseudomonas aeruginosa infection: a hospital-based case-control study. Arch AHS [Internet]. 2021 Aug. 15 [cited 2024 May 3];33(2):48-55. Available from: https://he01.tci-thaijo.org/index.php/ams/article/view/219028
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Vol. 33 No. 2 (2021): May - August
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Original article
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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