Comprehensive Strategies to Mitigate PM 2.5-Induced Lung Cancer and Address Public Health Challenges
Keywords:
air pollution, indoor environmental exposure, lung cancer, particulate matter pollution, respiratory tract diseasesAbstract
Particulate matter (PM2.5) pollution poses a significant global health challenge, linked to adverse respiratory outcomes and increased lung cancer mortality. Although researchers widely acknowledge this association, they have limited understanding of how PM2.5 concentration and socioeconomic factors influence the spatial dynamics of lung cancer incidence. Research in eastern China and Brazil highlights the correlation between PM2.5 exposure, education levels and heightened cancer mortality risk. However, clear strategies to prevent lung cancer caused by PM2.5 are still lacking and require a thorough synthesis of evidence. Effective management and prevention of PM2.5-induced lung cancer require a holistic approach, encompassing health education, personalized symptom management, regular monitoring, smoking cessation support, environmental modifications, comprehensive care coordination and public health advocacy. By implementing these evidence-based strategies, healthcare providers can mitigate the adverse health effects of PM2.5 pollution and promote respiratory health globally. In conclusion, addressing PM2.5 pollution and its association with lung cancer mortality demands a multifaceted approach, emphasizing collaboration and evidence-based interventions to improve public health outcomes.
References
Tomar G, Nagpure AS, Jain Y, Kumar V. High-resolution PM2.5 emissions and associated health impact inequalities in an Indiandistrict. Environ Sci Technol. 2023;57:2310-21.
Wang Y, Zhong Y, Liao J, Wang G. PM2.5-related cell death patterns. Int J Med Sci. 2021;18:1024-29.
Guo B, Gao Q, Pei L, Guo T, Wang Y, Wu H, et al. Exploring the association of PM2.5 with lung cancer incidence under different climate zones and socioeconomic conditions from 2006 to 2016 in China. Environ Sci Pollut Res Int. 2023;30:126165-77.
Yu P, Xu R, Li S, Coelho MSZS, Saldiva PHN, Sim MR, et al. Associations between long-term exposure to PM2.5 and site-specific cancer mortality: a nationwide study in Brazil between 2010 and 2018. Environ Pollut. 2022;302:119070.
Xing YF, Xu YH, Shi MH, Lian YX. The impact of PM2.5 on the human respiratory system. J Thorac Dis. 2016;8:E69-74.
Barbier E, Carpentier J, Simonin O, Gosset P, Platel A, Happillon M, et al. Oxidative stress and inflammation induced by air pollution-derived PM2.5 persist in the lungs of mice after cessation of their sub-chronic exposure. Environ Int. 2023;181:108248.
Wang S, Zhou Q, Tian Y, Hu X. The lung microbiota affects pulmonary inflammation and oxidative stress induced by PM2.5 exposure. Environ Sci Technol. 2022;56:12368-79.
Li Y, Batibawa JW, Du Z, Liang S, Duan J, Sun Z. Acute exposure to PM2.5 triggers lung inflammatory response and apoptosis in rat. Ecotoxicol Environ Saf. 2021;222:112526.
Jin Y, Li Y, He S, Ge Y, Zhao Y, Zhu K, et al. ATM participates in fine particulate matter-induced airway inflammation through regulating DNA damage and DNA damage response. Environ Toxicol. 2023;38:2668-78.
Li R, Zhou R, Zhang J. Function of PM2.5 in the pathogenesis of lung cancer and chronic airway inflammatory diseases. Oncol Lett. 2018;15:7506-14.
Lim JU, Yoon HK. Narrative review: association between lung cancer development and ambient particulate matter in never-smokers. J Thorac Dis. 2022;14:553-63.
Li J, Lu X, Liu F, Liang F, Huang K, Yang X, et al. Chronic effects of high fine particulate matter exposure on lung cancer in China. Am J Respir Crit Care Med. 2020;202:1551-9.
Nakharutai N, Traisathit P, Thongsak N, Supasri T, Srikummoon P, Thumronglaohapun S, et al. Impact of residential concentration of PM2.5 analyzed as time-varying covariate on the survival rate of lung cancer patients: a 15-year hospital-based study in upper northern Thailand. Int J Environ Res Public Health. 2022;19:4521.
Chen J, Hoek G. Long-term exposure to PM and all-cause and cause-specific mortality: A systematic review and meta-analysis. Environ Int. 2020;143:105974.
Yu P, Xu R, Coelho MSZS, Saldiva PHN, Li S, Zhao Q, et al. The impacts of long-term exposure to PM2.5 on cancer hospitalizations in Brazil. Environ Int. 2021;154:106671.
Bouchriti Y, Korrida A, Haddou MA, Achbani A, Sine H, Rida J, et al. Mortality and morbidity assessment attributed to short- and long-term exposure to fine particles in ambient air of Agadir city, Morocco: the AirQ model approach. Environ Anal Health Toxicol. 2023;38:e2023009-0.
McDonnell WF, Nishino-Ishikawa N, Petersen FF, Chen LH, Abbey DE. Relationships of mortality with the fine and coarse fractions of long-term ambient PM10 concentrations in nonsmokers. J Expo Anal Environ Epidemiol. 2000;10:427-36.
Pope CA, 3rd, Burnett RT, Turner MC, Cohen A, Krewski D, Jerrett M, Gapstur SM, Thun MJ. Lung cancer and cardiovascular disease mortality associated with ambient air pollution and cigarette smoke: shape of the exposure-response relationships. Environ Health Perspect. 2011;119:1616-21
Hart JE, Garshick E, Dockery DW, Smith TJ, Ryan L, Laden F. Long-term ambient multipollutant exposures and mortality. Am J Respir Crit Care Med. 2011;183:73-8
Lipsett MJ, Ostro BD, Reynolds P, Goldberg D, Hertz A, Jerrett M, et al. Long-term exposure to air pollution and cardiorespiratory disease in the California teachers study cohort. Am J Respir Crit Care Med. 2011;184:828-35.
Lepeule J, Laden F, Dockery D, Schwartz J. Chronic exposure to fine particles and mortality: an extended follow-up of the Harvard Six Cities study from 1974 to 2009. Environ Health Perspect. 2012;120:965-70.
Hystad P, Demers PA, Johnson KC, Carpiano RM, Brauer M. Long-term residential exposure to air pollution and lung cancer risk. Epidemiology. 2013;24:762-72.
Puett RC, Hart JE, Yanosky JD, Spiegelman D, Wang M, Fisher JA, et al. Particulate matter air pollution exposure, distance to road, and incident lung cancer in the nurses’ health study cohort. Environ Health Perspect. 2014;122:926-32.
Hart JE, Spiegelman D, Beelen R, Hoek G, Brunekreef B, Schouten LJ, et al. Long-Term Ambient Residential Traffic-Related Exposures and Measurement Error-Adjusted Risk of Incident Lung Cancer in the Netherlands Cohort Study on Diet and Cancer. Environ Health Perspect. 2015; 123:860-66.
Weichenthal S, Crouse DL, Pinault L, Godri-Pollitt K, Lavigne E, Evans G, et al. Oxidative burden of fine particulate air pollution and risk of cause-specific mortality in the Canadian Census Health and Environment Cohort (CanCHEC). Environ Res. 2016;146:92-9.
Gharibvand L, Shavlik D, Ghamsary M, Beeson WL, Soret S, Knutsen R, et al. The association between ambient fine particulate air pollution and lung cancer incidence: results from theAHSMOG-2 study Environ. Health Perspect. 2016;125:378–84
Tomczak A, Miller AB, Weichenthal SA, To T, Wall C, Donkelaar AV, et al. Long-term exposure to fine particulate matter air pollution and the risk of lung cancer among participants of the Canadian national breast screening study. Int. J. Cancer 2016;139:1958-66
Beelen R, Hoek G, van den Brandt PA, Goldbohm RA, Fischer P, Schouten LJ, et al. Long-term effects of traffic-related air pollution on mortality in a Dutch cohort (NLCS-AIR study). Environ Health Perspect. 2008;116:196-202.
Carey IM, Atkinson RW, Kent AJ, van Staa T, Cook DG, Anderson HR. Mortality associations with long-term exposure to outdoor air pollution in a national English cohort. Am J Respir Crit Care Med. 2013;187:1226-33.
Cesaroni G, Badaloni C, Gariazzo C, Stafoggia M, Sozzi R, Davoli M, et al. Long-term exposure to urban air pollution and mortality in a cohort of more than a million adults in Rome. Environ Health Perspect. 2013; 121:324-31.
Raaschou-Nielsen O, Andersen ZJ, Beelen R, Samoli E, Stafoggia M, Weinmayr G, et al. Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE). Lancet Oncol. 2013;14:813-22.
Cao J, Yang C, Li J, Chen R, Chen B, Gu D, et al. Association between long-term exposure to outdoor air pollution and mortality in China: a cohort study. J Hazard Mater. 2011;186:1594-600.
Katanoda K, Sobue T, Satoh H, Tajima K, Suzuki T, Nakatsuka H, et al. An association between long-term exposure to ambient air pollution and mortality from lung cancer and respiratory diseases in Japan. J Epidemiol. 2011;21:132-43.
Yorifuji T, Bae S, Kashima S, Tsuda T, Doi H, Honda Y, et al. Health Impact Assessment of PM10 and PM2.5 in 27 Southeast and East Asian Cities. J Occup Environ Med. 2015;57:751-6.
Guo Y, Zeng H, Zheng R, Li S, Barnett AG, Zhang S, et al. The association between lung cancer incidence and ambient air pollution in China: A spatiotemporal analysis. Environ Res. 2016;144:60-5.
Sett MJ, Ostro BD, Reynolds P, Goldberg D, Hertz A, Jerrett M, et al. Long-term exposure to air pollution and cardiorespiratory disease in the California teachers study cohort. Am J Respir Crit Care Med. 2011;184:828-35.
Wang Y, Zhong H. Mitigation strategies for controlling urban particulate pollution from traffic congestion: road expansion and road public transport. J Environ Manage. 2023;345:118795.
Duan W, Wang X, Cheng S, Wang R. A new scheme of PM2.5 and O3 control strategies with the integration of SOM, GA and WRF-CAMx. J Environ Sci (China). 2024;138:249-65.
Kim H, Huh JY, Na G, Park S, Ra SW, Kang SY, et al. Lifestyle practices that reduce seasonal PM2.5 exposure and their impact on COPD. Sci Rep. 2023;13:11822.
Ling H, Qing L, Jian X, Lishu S, Liang L, Qian W, et al. Strategies towards PM2.5 attainment for non-compliant cities in China: a case study. J Environ Manage. 2021;298:113529.
Expert Consensus Task Force, Shi X, Duan G. Recommendations of controlling and preventing acute health risks of fine particulate matter pollution - China, 2021. China CDC Wkly. 2022;4:329-4
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