Melanoma in situ on nose : A case report
Abstract
A 59-years-old woman, who was also an accountant. The patient had a pigmented lesion present on her tip of nose for ten years then the lesion appeared larger. She had been following with dermatologist. Superficial shave biopsy was done and pathological report of part of melanoma in situ, at least. The dermatologist made a cancer hospital referral. Full thickness incisional biopsy was done and pathological report of basal hyperpigmentation and scattered basal melanophages. The lesion was excised with a 7 mm. margin and pathological report of hyperpigmentation of basal keratinocytes and no abnormal melanocytic proliferation. Finally, pathological diagnosis after wide excision revealed melanoma in situ. The patient has not been recurred after 2 years of treatment
References
Schmalbach CE, Durham AB, Johnson TM, Bradford CR. Management of cutaneous head and neck melanoma. In: Cummings CW, Flint PW, Francis HW, Hughey BH, Lesperance MM, editors. Cummings Otolaryngology head and neck surgery. 7thed. St. Louis, MO: Mosby; 2021. p. 4375-428.
Abbasi NR, Shaw HM, Rigel DS, Friedman RJ, McCarthy WH, Osman I, et al. Early diagnosis of cutaneous melanoma: revisiting the ABCD criteria. JAMA 2004;292:2771-6.
British association of dermatologists. Melanoma in situ. What is melanoma in situ? [Internet]. London: Dermatology department, Addenbrookes Hospital; 2011 [cited 2021 Oct 15]. Available from: http://www.bad.org.uk/shared/get-file. ashx?id=2126&itEmtyPe=document.
Megahed M, Schön M, Selimovic D, Schön MP. Reliability of diagnosis of melanoma in situ. Lancet 2002;359:1921-2.
Natsupa Wiriyakulsit, Patcharee Klomkleang, Thanet Sornda, Worasak Kaewkong. Melanoma: Incidence among the Thai population and the use of a molecular understanding of this cancer to improve the strategy of targeted therapy. Thai cancer journal 2021;41:134-48.
Mocellin S , Nitti D. Cutaneous melanoma in situ: translational evidence from a large population based study.The oncologist 2011;16:896903.
National Comprehensive Cancer Network. Cutaneous Melanoma [Internet]. 2021 [cited2021 Nov 20]. Available from: https://www.nccn.org/professionals/ physician_gls/pdf/cutaneous_melanoma.pdf.
Abbasi NR, Yancovitz M, Gutkowicz-Krusin D, Panageas KS, Mihm MC, Googe P, et al. Utility of lesion diameter in the clinical diagnosis of cutaneous melanoma. JAMA dermatology 2008;144:469-74.
Egnatios GL, Dueck AC, Macdonald JB, Gray RJ, Wasif N, Pockaj BA, et al. The impact of biopsy technique on upstaging, residual disease, and outcome in cutaneous melanoma. American journal of surgery 2011;202:771-8.
Ohsie SJ, Sarantopoulos GP, Cochran AJ, Binder SW. Immunohistochemical characteristics of melanoma. Journal of cutaneous pathology 2008;35:433–44.
Moore P, Hundley J, Shen P, Levine EA, Williford P, Sangueza O, et al. Does shave biopsy accurately predict the final Breslow depth of primary cutaneous melanoma? American surgeon 2009;75:369–73.
Ng PC, Barzilai DA, Ismail SA, Gilliam AC. Evaluating invasive cutaneous melanoma: Is the initial biopsy representative of the final depth? Journal of the American academy dermatology 2003;48:420-4.
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