Risk factors of systemic inflammatory response syndrome following retrograde intrarenal surgery for renal and upper ureteric stones in Trang hospital , Thailand

Main Article Content

Channarong Warotamawit

Abstract

Objective :Retrograde intrarenal surgery (RIRS ) has many complications . This study aimed to evaluate the risk factors of systemic inflammatory response syndrome (SIRS)  following retrograde intrarenal surgery.


 


Method  :This study retrospectively analyzed 48 patients who underwent RIRS between January 2020 to July 2023 at Trang hospital.  All RIRS were conducted with patients under general anesthesia in the low lithotomy position and performed by 1 urologist. Preoperative and intraoperative risk factors that potentially contribute to SIRS were compared in patients who developed postoperative SIRS and those who did not. Univariable ( two way analysis of variance ) and multivariable analysis ( one way multivariate analysis of variance ) was done. The level of significance was set at p-value <0.05.


 


Results :The incidence of SIRS following RIRS was 47.9% . In univariate test analysis, significant between SIRS and three factors was noted : BMI ≥25 kg/m2 , longer operative time ≥ 90 minutes and preoperative positive urine culture were likely to have SIRS (p=0.002 , p=0.021 , p=0.000 respectively ). In multivariate analysis confirmed that BMI ≥25 kg/m2 , longer operative time ≥ 90 minutes and preoperative positive urine culture results (p=0.044,p=0.040,p=0.001 respectively ) were significant risk factors of SIRS following RIRS procedure .


 


Conclusion :The patients with BMI ≥25 kg/m2  , operative time ≥ 90 minutes or preoperative positive urine culture resuts should be concerned about SIRS following RIRS procedure.


 

Article Details

How to Cite
1.
Warotamawit C. Risk factors of systemic inflammatory response syndrome following retrograde intrarenal surgery for renal and upper ureteric stones in Trang hospital , Thailand. Kb. Med. J. [Internet]. 2023 Dec. 1 [cited 2024 Nov. 13];6(2):57-66. Available from: https://he01.tci-thaijo.org/index.php/KBJ/article/view/265921
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Original Article

References

Basatac C, Ozman O, Çakır H, Çınar O, Akgul HM, Sıddıkoglu D, et al. Retrograde intrarenal surgery is a safe procedure in severe obese patients: Is it reality or prediction? A propensity score-matching analysis from RIRSearch Study Group. Journal of Endourology. 2022 Jul 1;36(7):891-7.

Cho SY, Choo MS, Jung JH, Jeong CW, Oh S, Lee SB, et al. Cumulative sum analysis for experiences of a single-session retrograde intrarenal stone surgery and analysis of predictors for stone-free status. Plos one. 2014 Jan 14;9(1):e84878

De S, Autorino R, Kim FJ, Zargar H, Laydner H, Balsamo R, et al. Percutaneous nephrolithotomy versus retrograde intrarenal surgery: a systematic review and meta-analysis. European urology. 2015 Jan 1;67(1):125-37.

Demir DO, Doluoglu OG, Yildiz Y, Bozkurt S, Ayyildiz A, Demirbas A. Risk factors for infectious complications in patients undergoing retrograde intrarenal surgery. J Coll Physicians Surg Pak. 2019 Jun 1;29(6):558-62.

Gao XS, Liao BH, Chen YT, Feng SJ, Gao R, Luo DY, et al. Different tract sizes of miniaturized percutaneous nephrolithotomy versus retrograde intrarenal surgery: a systematic review and meta-analysis. Journal of Endourology. 2017 Nov 1;31(11):1101-10.

Kim DS, Yoo KH, Jeon SH, Lee SH. Risk factors of febrile urinary tract infections following retrograde intrarenal surgery for renal stones. Medicine. 2021 Apr 4;100(13).

Kwon YE, Oh DJ, Kim MJ, Choi HM. Prevalence and clinical characteristics of asymptomatic pyuria in chronic kidney disease. Annals of laboratory medicine. 2020 May;40(3):238-44.

Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, et al. 2001 sccm/esicm/accp/ats/sis international sepsis definitions conference. Critical care medicine. 2003 Apr 1;31(4):1250-6.

Mancini V, Cormio L, d’Altilia N, Benedetto G, Ferrarese P, Balzarro M, et al. Retrograde intrarenal surgery for symptomatic renal sinus cysts: long-term results and literature review. Urologia Internationalis. 2018 Aug 22;101(2):150-5.

McDougal WS, Wein AJ, Kavoussi LR, Partin AW, Peters CA. Campbell-Walsh Urology 11th Edition Review E-Book. Elsevier Health Sciences; 2015 Sep 25.

Skolarikos A, Neisius A, Petrík A, Somani B, Thomas K, Gambaro G, et al. InEAU Guidelines. Edn. presented at the EAU Annual Congress Amsterdam 2022.

Takayasu H, Aso Y, Takagi T, Go T. Fiberoptic pyeloureteroscope. Surgery. 1971;70:661-3.

Zhang H, Jiang T, Gao R, Chen Q, Chen W, Liu C, et al. Risk factors of infectious complications after retrograde intrarenal surgery: a retrospective clinical analysis. Journal of International Medical Research. 2020 Sep;48(9):0300060520956833.

Zhong W, Leto G, Wang L, Zeng G. Systemic inflammatory response syndrome after flexible ureteroscopic lithotripsy: a study of risk factors. Journal of Endourology. 2015 Jan 1;29(1):25-8.