Correlation factors of severity in non-variceal upper gastrointestinal bleeding in Krabi Hospital

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Nattawat Wanich


Background: Peptic ulcers with high-risk stigmata features carry high mortality rate due to rebleeding conditions and need for urgent endoscopic hemostasis procedure. This study aimed to develop a simple tool to determine any correlation factors with high-risk stigmata features of peptic ulcers in pre-endoscopic non-variceal upper gastrointestinal bleeding patients.

Methods: This research involved a retrospective review of pre-endoscopic data from 100 patients with peptic ulcer bleeding from 1 August 2019 – 31 August 2021 at Krabi Hospital. Demographic, clinical presentation and laboratory data were compared between high-risk and low-risk stigmata peptic ulcer groups. The model scoring system was determined by using logistic regression and ROC curve to come up with a simple predictor tool that could identify high-risk stigmata of non-variceal upper gastrointestinal bleeding.

Result: Statistically significant factors were albumin < 3 g/dL, mean arterial pressure (MAP) < 80 mmHg, heart rate ≥ 90 /min and presence of fresh blood in nasogastric. Prediction Model and Scoring Algorithm for high risk stigmata cut off was 7 points with sensitivity of 78.79% and specificity of 73.13%. The area under ROC curve was 0.7596.

Conclusion: This study revealed albumin < 3 g/dL, mean arterial pressure (MAP) < 80 mmHg, heart rate ≥ 90 /min and presence of fresh blood in nasogastric correlation factors with high-risk stigmata of peptic ulcers in non-variceal upper gastrointestinal bleeding. The findings of this study can be used as a new pre-endoscopic predictor tool for identifying patients at high risk of rebleeding.

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How to Cite
Wanich N. Correlation factors of severity in non-variceal upper gastrointestinal bleeding in Krabi Hospital. Kb. Med. J. [Internet]. 2023 Jul. 18 [cited 2024 Apr. 19];6(1):25-3. Available from:
Original Article


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