Factors Associated with Vaginal Infections in Pregnant Women with Preterm Labor at the Government Hospital
Keywords:
vaginal infection, preterm labor, pregnancy, pregnancy history, health historyAbstract
This retrospective analytical study aimed to investigate the prevalence and associated factors of vaginal infection among pregnant women with preterm labor. The study sample comprised 327 pregnant women who were admitted to a hospital. Data were collected from medical records using a structured data collection form and analyzed with descriptive statistics and the chi-square test. The findings revealed that the prevalence of vaginal infection in pregnant women with preterm labor was 42.8%. Statistically significant factors associated with vaginal infection included substance use ( = 6.782, p = .014) and body mass index (
= 6.920, p = .048). In contrast, other general characteristics such as age, educational level, and occupation were not significantly associated. These findings highlight the need for early screening of pregnant women with such risk factors during antenatal care, as well as the development of policies and nursing guidelines focusing on health promotion, substance use reduction, and nutritional management to prevent vaginal infections and reduce the risk of preterm birth.
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References
Mikula F, Wimmer M, Farr A, Leitich H, Ebner J, Grill A, et al. Vaginal Microbial Colonization after Antibiotic Treatment in Women with Preterm Premature Rupture of Membranes: An Observational Cohort Study. Journal of Clinical Medicine. 2023;12(23):1-12.
Sethi N, Narayanan V, Saaid R, Ahmad Adlan AS, Ngoi ST, Teh CSJ, et al. Prevalence, risk factors, and adverse outcomes of bacterial vaginosis among pregnant women: a systematic review. BioMed Central Pregnancy and Childbirth. 2025;25(1):1-13.
Yao D, Tang X, Xue M, Zhu K, Li W, Chen Z, et al. The effects of vaginal infections on pregnancy outcomes: a retrospective cohort study in China. BioMed Central Pregnancy Childbirth. 2025;25(1):1-15.
Gigi RMS, Buitrago-Garcia D, Taghavi K, Dunaiski CM, van de Wijgert J, Peters RPH, et al. Vulvovaginal yeast infections during pregnancy and perinatal outcomes: systematic review and meta-analysis. BioMed Central Womens Health. 2023;23(1):1-12.
Daskalakis G, Psarris A, Koutras A, Fasoulakis Z, Prokopakis I, Varthaliti A, et al. Maternal Infection and Preterm Birth: From Molecular Basis to Clinical Implications. Children (Basel). 2023;10(5):1-17.
Mathew SM, & Kumar A. A prospective analysis of the risk factors and the perinatal outcome of preterm labour. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2018;7(12):4833-40.
Huang C, Gin C, Fettweis J, Foxman B, Gelaye B, MacIntyre DA, et al. Meta-analysis reveals the vaginal microbiome is a better predictor of earlier than later preterm birth. BioMed Central Biology. 2023;21(1):1-16.
Ohuma EO, Moller A-B, Bradley E, Chakwera S, Hussain-Alkhateeb L, Lewin A, et al. National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis. The Lancet. 2023;402(10409):1261-71.
Chawanpaiboon S, Vogel JP, Moller A-B, Lumbiganon P, Petzold M, Hogan D, et al. Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. The Lancet Global Health. 2019;7(1):e37-e46.
Department of Medical Services Ministry of Public Health. Guidelines for prevention of preterm labor in Thailand. Bangkok: Ministry of Public Health; 2023. (in Thai)
Djogic LM, Cehic E, Hodzic H, Babic A, & Sljivo B. Prevalence of Bacterial Vaginosis of Pregnant Women in the General Hospital Tesanj. Medical Archives. 2025;79(3):194-8.
Ahmed M, Admassu Ayana D, & Abate D. Bacterial vaginosis and associated factors among pregnant women attending antenatal care in Harar City, Eastern Ethiopia. Infection and Drug Resistance. 2022:3077-86.
Froehle L, Ghanem KG, Page K, Hutton HE, Chander G, Hamill MM, et al. Bacterial vaginosis and alcohol consumption: a cross-sectional retrospective study in Baltimore, Maryland. Sexually transmitted diseases. 2021;48(12):986-90.
Saengsuwan D, & Anusornteerakul S. Prevalence of Methamphetamine Use and Health Promotion Behaviors among Pregnant Women at Antenatal Clinic of the Subdistrict Health Promotion Hospital in Mueang Udonthani District. Journal of The Royal Thai Army Nurses. 2024;25(2):92-100. (in Thai)
O’Connor A, Harris D, Seeber D, Hamilton D, Fisher P, & Sachmann D. Methamphetamine use in pregnancy, Child Protection, and Removal of infants: Tertiary Centre Experience from Western Australia. Midwifery. 2020; 83:102641-47.
Qi J, Han H, Li X, & Ren Y. Association between body mass index and prevalence of bacterial vaginosis: Results from the NHANES 2001–2004 study. Plos one. 2024;19(5):e0296455-62.
Brookheart RT, Lewis WG, Peipert JF, Lewis AL, & Allsworth JE. Association between obesity and bacterial vaginosis as assessed by Nugent score. American journal of obstetrics and gynecology. 2019;220(5):476. e1-. e11.
Lokken EM, Richardson BA, Kinuthia J, Mwinyikai K, Abdalla A, Jaoko W, et al. A Prospective Cohort Study of the Association Between Body Mass Index and Incident Bacterial Vaginosis. Sexually Transmitted Diseases. 2019;46(1): 31-6.
Raksatham C, Kaipho T, & Khungtumneam K. The Practiced Guideline for Continuing Care of Pregnant Women with Preterm Labor. Journal of The Royal Thai Army Nurses. 2018;19(0): 348-56. (in Thai)
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