Factors Predicting Immunosuppressive Medication Adherence in Kidney Transplant Persons
Keywords:
Immunosuppressive medication adherence, Kidney transplant, predicting factorAbstract
This predictive correlational study aims to examine adherence to immunosuppressive medication (ISM) and the predictive factors influencing ISM adherence among kidney transplant persons. The study sample consists of 113 kidney transplant persons, aged 18 years and older, from the Kidney Transplant Clinic in a tertiary-level government hospitals in Bangkok. Data are collected by using eight questionnaires, including: Demographic data questionnaire, ISM questionnaire, comorbidity questionnaire, social support questionnaire, perceived susceptibility to kidney rejection questionnaire, perceived severity of kidney rejection questionnaire, perceived benefits of ISM questionnaire, and perceived barriers to ISM questionnaire. The results revealed that: 1) The participants demonstrated a high level of ISM adherence, with an average score of 23.09 (SD = 0.84). 2) The predictive factors influencing to ISM adherence among kidney transplant persons included time after transplantation, social support, perceived barriers to ISM, and perceived susceptibility of kidney rejection. These factors account for 31.40% of the variance in ISM adherence among kidney transplant persons (Adjusted R² = 0.314, p < .05).
Downloads
References
Arpornsujaritkun N, Kantachuvesiri S, & Jirasiritham S. Kidney transplantation. Bangkok: Ramathibodi Textbook Project;
(in Thai)
Osterberg L, & Blaschke T. Adherence to medication. The New England Journal of Medicine. 2005;353(5):487-97.
Sopitsakol U, Prapaipanich W, & Maneesriwongul W. Factors related to medication adherence in kidney transplant recipients. Ramathibodi Nursing Journal. 2018;24(3):328-34. (in Thai)
Gokoel SRM, Gombert-Handoko KB, Zwart TC, van der Boog PJM, Moes D, & de Fijter JW. Medication non-adherence after kidney transplantation: A critical appraisal and systematic review. Transplantation Reviews. 2020;34(1):1-7.
Phithakham C, Suttitong N, Kritsadathan T, Chailungkar N, Suyayai N, Manoree C, et al. Adherence to immunosuppressive drugs in kidney transplant recipients and factors associated with adherence. Lampang Medical Journal. 2022;43(2):60-70. (in Thai)
Kobayashi S, Tsutsui J, Okabe S, Hideki I, Akaho R, & Nishimura K. Medication nonadherence after kidney transplantation: An internetbased survey in Japan. Psychology, Health & Medicine. 2020;25(1):91-101.
Sornhiran P, Ingsathit A, Phakdeekitcharoen B, Sumethkul V, Kantachuvesiri S, Arpornsujaritkun N, et al. Effect of medication adherence on renal allograft outcome in postkidney transplant patients. Journal of the Nephrology Society of Thailand. 2021;27(3):68-81. (in Thai)
Zhang P, Zhu X, Yan J, & Liu J. Identification of immunosuppressive medication nonadherence factors through a combined theory model in renal transplant recipients. Frontiers in Pharmacology. 2021;12:655836.
Liu H, Shang Y, Du C, & Wu S. Immunosuppressive medication adherence and its associated factors in renal transplant recipients. Transplantation. 2018;102 (Supplement1) :S68.
Larpparisuth N, Cheungpasitporn W, & Lumpaopong A. Global perspective on kidney transplantation: Thailand. Kidney 360. 2021;2(7):1163-5.
Rosenstock IM. Historical Origins of the Health Belief Model. Health Education Monographs. 1974;2(4):328-35.
Thato R. Nursing Research: Concepts to Application (fifth edition). 6thed. Bangkok: Chulalongkorn University Press; 2022. (in Thai)
Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. NJ: Lawrence Erlbaum Associates; 1988.
Kusalaruk P, & Nakawiro D. A validity study of the Mini-Cog test in Thai dementia patients. Ramathibodi Nursing Journal. 2012;35(4): 264-71. (in Thai)
Choeichaiyapoom N, & Ua-kit N. Predicting factors of medication adherence among retreatment patients with pulmonary tuberculosis. (master’s thesis). Bangkok: Chulalongkorn University; 2012. (in Thai)
Charlson ME, Pompei P, Ales KL, & MacKenzie CR. A new method of classifying prognostic comorb id ity in long itud inal stud ies: Development and validation. Journal of Chronic Diseases. 1987;40(5):373-83.
Utriyaprasit K. The relationship between recovery symptoms and functional outcomes in Thai CABG patients. (doctoral dissertation). Cleveland (OH): Case Western Reserve University; 2001.
Surasrisakul I, & Ua-kit N. Predicting factors of medication adherence among myocardial infarct ion patients after underwent percutaneous coronary intervention. (master’s thesis). Bangkok: Chulalongkorn University; 2012. (in Thai)
Wangworatrakul W, Suwannaroop N, & Moopayak L. Factors predicting to medication adherence among patients with essential hypertension. Journal of The Royal Thai Army Nurses. 2017;18(1):131-9. (in Thai)
Kung P-C, Yeh MC, Lai M-K, & Liu HE. Renal transplant recipients: The factors related to immunosuppressive medication adherence based on the Health Belief Model. Journal of Nursing Research. 2017;25(5):392-7.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Journal of The Royal Thai Army Nurses
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
บทความหรือข้อคิดเห็นใดใดที่ปรากฏในวารสารพยาบาลทหารบกเป็นวรรณกรรมของผู้เขียน ซึ่งบรรณาธิการหรือสมาคมพยาบาลทหารบก ไม่จำเป็นต้องเห็นด้วย
บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของวารสารพยาบาลทหารบก
The ideas and opinions expressed in the Journal of The Royal Thai Army Nurses are those of the authors and not necessarily those
of the editor or Royal Thai Army Nurses Association.
