Effect of Synbiotic Supplementation on Defecation among Adults with Gastrointestinal Disorder


  • Nattakan Nin-on Department of Nutrition, Faculty of Public Health, Mahidol University
  • Promluck Sanporkha Department of Nutrition, Faculty of Public Health, Mahidol University
  • Suwimol Sapwarobol Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Chulalongkorn University
  • Chatrapa Hudthagosol Department of Nutrition, Faculty of Public Health, Mahidol University


Synbiotic, Defecation, Gastrointestinal disorder


Gastrointestinal infection can be caused by pathogenic contamination leading to an intestinal microflora imbalance and may lead to disease or other symptoms. Consequently, a modification that balances microflora in the gut is a good alternative for preventing disease or symptoms. This study is a randomized controlled trial, comparing the effect of synbiotic supplementation on stool frequency and stool consistency between intervention and placebo groups for 12 weeks. Self-reported bowel habits were made based on the Bristol Stool Scale. The statistical analysis included paired t-test to analyze data within groups, as well as independent t-test to analyze data between groups. In addition, the Chi-square test or Fisher’s exact test was used to analyze the difference in stool consistency. Results showed that stool frequency remained unchanged within and between groups.  However, stool consistency was significantly different between groups. Comparison between normal stools (Type 4-5) and abnormal stools (hard stool type 1-2 and loose stool type 6-7), the synbiotic supplementation group had a significantly higher normal stools than in the placebo group. This study concludes that synbiotic supplementation for 12 weeks does not affect stool frequency when compared within and between groups, but it significantly affected a change in stool consistency to an improved normal stool type.


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How to Cite

Nin-on, N., Sanporkha , P., Sapwarobol, S., & Hudthagosol, C. (2021). Effect of Synbiotic Supplementation on Defecation among Adults with Gastrointestinal Disorder. Journal of Nutrition Association of Thailand, 56(1), 26–36. Retrieved from https://he01.tci-thaijo.org/index.php/JNAT/article/view/245944



Research article