Drug-Resistant Tuberculosis Situation in New Thai and Non-Thai Patients in Public Health Region 5
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Abstract
This study was a 3-year retrospective study of new TB cases. Data were collected from October 1, 2018, to September 30, 2021, at the Disease Control Medical Laboratory, Office of Disease Prevention and Control, region 5 Ratchaburi. The data were analyzed to determine the rate of drug resistance in new cases of TB infection (bacteriologically confirmed TB case: B+) and compare the proportion of drug resistance detectable among Thai and non-Thai patients. The results showed that 6,957 new TB patients were diagnosed with tuberculosis, most of them aged between 25 and 59 years old, 6,080 cases of which were Thais, and 877 patients were non-Thais. There were 171 new cases of multidrug-resistant tuberculosis (Primary MDR-TB), representing 2.46 %. Primary MDR-TB included 147 Thais and 24 non-Thais, representing 2.42 % and 2.74 %, respectively. Among primary MDR-TB patients, nine cases were diagnosed with extensively drug-resistant TB (XDR-TB) and 7 cases of pre-extensively drug-resistant tuberculosis (Pre-XDR-TB), representing 5.26% and 4.09%, respectively. All nine cases of XDR-TB were Thai, while six cases of Pre-XDR-TB were Thai and the rest case was non-Thai. A comparison of the proportion of detection of TB drug resistance between Thai and non-Thai people was found with no difference (level of significance at 0.05).
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