Comparative Clinical Study of Cannabis Oil (Deja Formula) Versus Ibuprofen for the Treatment of Acute Migraine Patients: A Randomized Controlled Trial
Keywords:
DTAM ganja oil (Deja formula), Ibuprofen, Acute Migraine, Efficacy, SafetyAbstract
This study is a randomized controlled trial aiming to evaluate the efficacy and adverse effects of using cannabis oil (Deja's formulation) compared to ibuprofen in treating patients with acute migraine. The participants were acute migraine who received treatment at the Traditional and Complementary Medicine Hospital. The participants were randomly assigned into two groups: the experimental group, which received cannabis oil, and the control group, which received ibuprofen (200 mg /tablet), with 33 participants in each group. The findings revealed that the average age of the participants was 37 years (sd= years), and most of them were female (90.90%). When comparing pre- and post-treatment within the same group, the experimental group showed a significant reduction in the frequency, severity, and duration of migraine headaches (p<0.05). The control group also showed a significant reduction in frequency and severity of pain (p<0.05), but the duration of pain did not significantly difference (p=0.277). When comparing the two groups post-treatment, there was no significant difference in effectiveness between cannabis oil and ibuprofen in reducing the frequency (p=0.563), duration (p=0.964), and severity of pain (p=0.051). The study concludes that cannabis oil can reduce the frequency, duration, and severity of acute migraine headaches as effective as standard medication. However, careful dosage control is recommended to minimize the risk of side effects and adverse events.
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