Embolic Strokes of Undetermined Source
คำสำคัญ:
โรคหลอดเลือดสมองอุดตันจากลิ่มเลือดที่ไม่ทราบสาเหตุแน่ชัดบทคัดย่อ
โรคหลอดเลือดสมองอุดตันจากลิ่มเลือดที่ไม่ทราบสาเหตุแน่ชัดเป็นโรคสมองขาดเลือดที่ไม่ได้เป็นแบบ lacune และน่าจะมีสาเหตุจากลิ่มเลือดอุดตันแต่ตรวจไม่พบแหล่งที่มา ของลิ่มเลือดนั้นหลังได้รับการตรวจทางหัวใจและหลอดเลือดแล้ว, ปัจจุบันยังไม่มีแนวทางการ รักษาที่ชัดเจน ในผู้ป่วยกลุ่มนี้แต่กำลังมีการศึกษาเพื่อหาแนวทางป้องกันการกลับเป็นซ้ำ ที่เหมาะสม
เอกสารอ้างอิง
Grau AJ, Weimar C, Buggle F, Heinrich A, Goertler M, Neumaier S, et al. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German
stroke data bank. Stroke (2001) 32(11):2559–66.
Putaala J, Metso AJ, Metso TM, Konkola N, Kraemer Y, Haapaniemi E, et al. Analysis of 1008 consecutive patients aged 15 to 49 with first-ever ischemic stroke the Helsinki young stroke registry. Stroke (2009) 40(4):1195–203.
Li L, Yiin GS, Geraghty OC, Schulz UG, Kuker W, Mehta Z, et al. Incidence, outcome, risk factors, and long-term prognosis of cryptogenic transient ischaemic
attack and ischaemic stroke: a population-based study. The Lancet Neurology (2015) 14(9):903–13.
Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a
multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 24 (1993) 1:35–41.
Hart RG, Diener HC, Coutts SB, Easton JD, Granger CB, O’Donnell MJ, et al. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol (2014) 13(4):429–38.
Gladstone DJ, Spring M, Dorian P, et al. Atrial fibrillation in patients with cryptogenic stroke. N Engl J Med 2014; 370:2467–2477.
Sanna T, Diener HC, Passman RS, et al. Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med 2014; 370:2478–2486.
Brambatti M, Connolly SJ, Gold MR, et al. Temporal relationship between subclinical atrial fibrillation and embolic events. Circulation 2014; 129:2094–2099.
Sposato LA, Cipriano LE, Riccio PM, et al. Very short paroxysms account for more than half of the cases of atrial fibrillation detected after stroke and
TIA: a systematic review and meta-analysis. Int J Stroke 2015; 10:801–807.
Ntaios G, Papavasileiou V, Milionis H, et al. Embolic strokes of undetermined source in the Athens stroke registry: an outcome analysis. Stroke 2015; 46:2087–2093.
McGrath ER, Paikin JS, Motlagh B, et al. Transesophageal echocardiography in patients with cryptogenic ischemic stroke: a systematic review. Am Heart J 2014; 168:706–712.
Jauss M, Zanette E. Detection of right-to-left shunt with ultrasound contrast agent and transcranial Doppler sonography. Cerebrovasc Dis 2000; 10: 490–496.
Kraywinkel K, Gortler M, Haass AH, et al. D i a g n o s t i c b e n e fi t o f t r a n s e s o p h a g e a l echocardiography after TIA and ischemic stroke. Aktuelle Neurol 2005; 32:129–135.
Alsheikh-Ali AA, Thaler DE, Kent DM. Patent foramen ovale in cryptogenic stroke: incidental or pathogenic? Stroke 2009; 40:2349–2355.
Furlan AJ, Reisman M, Massaro J, et al. Closure or medical therapy for cryptogenic stroke with patent foramen ovale. N Engl J Med 2012; 366:991–999.
Carroll JD, Saver JL, Thaler DE, et al. Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. N Engl J Med 2013; 368:1092–1100.
Meier B, Kalesan B, Mattle HP, et al. Percutaneous closure of patent foramen ovale in cryptogenic embolism. N Engl J Med 2013; 368:1083–1091.
Kent DM, Dahabreh IJ, Ruthazer R, et al. Device Closure of Patent Foramen Ovale After Stroke: Pooled Analysis of Completed Randomized Trials.
J Am Coll Cardiol 2016; 67(8):907-17.
Kent DM, Ruthazer R, Weimar C, et al. An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke. Neurology 2013; 81:
619–625.
Freilinger TM, Schindler A, Schmidt C, et al. Prevalence of nonstenosing, complicated atherosclerotic plaques in cryptogenic stroke. JACC Cardiovasc Imaging 2012; 5:397–405.
Amarenco P, Davis S, Jones EF, et al. Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques. Stroke 2014; 45:1248–1257.
Wehrum T, Kams M, Strecker C, et al. Prevalence of potential retrograde embolization pathways in the proximal descending aorta in stroke patients and
controls. Cerebrovasc Dis 2014; 38:410–417.
Mas JL, Arquizan C, Lamy C, et al. Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med 2001; 345:1740–1746.
Sacco RL, Prabhakaran S, Thompson JL, et al. Comparison of warfarin versus aspirin for the prevention of recurrent stroke or death: subgroup
analyses from theWarfarin-Aspirin Recurrent Stroke Study.Cerebrovasc Dis 2006; 22:4–12.
Halkes PH, van Gijn J, Kappelle LJ, et al. Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT):
a randomized controlled trial. Lancet Neurol 2007; 6:115–124.
Clinical trials. (2017). Available from: https://clinicaltrials.gov/ct2/show/ NCT02239120. Accessed 1 January 2017.
Clinical trials. (2017). Available from: https://clinicaltrials.gov/ct2/show/ NCT02313909. Accessed 1 January 2017.
Clinical trials. (2017). Available from: https://clinicaltrials.gov/ct2/show/ NCT02427126. Accessed 1 January 2017.
stroke data bank. Stroke (2001) 32(11):2559–66.
Putaala J, Metso AJ, Metso TM, Konkola N, Kraemer Y, Haapaniemi E, et al. Analysis of 1008 consecutive patients aged 15 to 49 with first-ever ischemic stroke the Helsinki young stroke registry. Stroke (2009) 40(4):1195–203.
Li L, Yiin GS, Geraghty OC, Schulz UG, Kuker W, Mehta Z, et al. Incidence, outcome, risk factors, and long-term prognosis of cryptogenic transient ischaemic
attack and ischaemic stroke: a population-based study. The Lancet Neurology (2015) 14(9):903–13.
Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a
multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 24 (1993) 1:35–41.
Hart RG, Diener HC, Coutts SB, Easton JD, Granger CB, O’Donnell MJ, et al. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol (2014) 13(4):429–38.
Gladstone DJ, Spring M, Dorian P, et al. Atrial fibrillation in patients with cryptogenic stroke. N Engl J Med 2014; 370:2467–2477.
Sanna T, Diener HC, Passman RS, et al. Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med 2014; 370:2478–2486.
Brambatti M, Connolly SJ, Gold MR, et al. Temporal relationship between subclinical atrial fibrillation and embolic events. Circulation 2014; 129:2094–2099.
Sposato LA, Cipriano LE, Riccio PM, et al. Very short paroxysms account for more than half of the cases of atrial fibrillation detected after stroke and
TIA: a systematic review and meta-analysis. Int J Stroke 2015; 10:801–807.
Ntaios G, Papavasileiou V, Milionis H, et al. Embolic strokes of undetermined source in the Athens stroke registry: an outcome analysis. Stroke 2015; 46:2087–2093.
McGrath ER, Paikin JS, Motlagh B, et al. Transesophageal echocardiography in patients with cryptogenic ischemic stroke: a systematic review. Am Heart J 2014; 168:706–712.
Jauss M, Zanette E. Detection of right-to-left shunt with ultrasound contrast agent and transcranial Doppler sonography. Cerebrovasc Dis 2000; 10: 490–496.
Kraywinkel K, Gortler M, Haass AH, et al. D i a g n o s t i c b e n e fi t o f t r a n s e s o p h a g e a l echocardiography after TIA and ischemic stroke. Aktuelle Neurol 2005; 32:129–135.
Alsheikh-Ali AA, Thaler DE, Kent DM. Patent foramen ovale in cryptogenic stroke: incidental or pathogenic? Stroke 2009; 40:2349–2355.
Furlan AJ, Reisman M, Massaro J, et al. Closure or medical therapy for cryptogenic stroke with patent foramen ovale. N Engl J Med 2012; 366:991–999.
Carroll JD, Saver JL, Thaler DE, et al. Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. N Engl J Med 2013; 368:1092–1100.
Meier B, Kalesan B, Mattle HP, et al. Percutaneous closure of patent foramen ovale in cryptogenic embolism. N Engl J Med 2013; 368:1083–1091.
Kent DM, Dahabreh IJ, Ruthazer R, et al. Device Closure of Patent Foramen Ovale After Stroke: Pooled Analysis of Completed Randomized Trials.
J Am Coll Cardiol 2016; 67(8):907-17.
Kent DM, Ruthazer R, Weimar C, et al. An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke. Neurology 2013; 81:
619–625.
Freilinger TM, Schindler A, Schmidt C, et al. Prevalence of nonstenosing, complicated atherosclerotic plaques in cryptogenic stroke. JACC Cardiovasc Imaging 2012; 5:397–405.
Amarenco P, Davis S, Jones EF, et al. Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques. Stroke 2014; 45:1248–1257.
Wehrum T, Kams M, Strecker C, et al. Prevalence of potential retrograde embolization pathways in the proximal descending aorta in stroke patients and
controls. Cerebrovasc Dis 2014; 38:410–417.
Mas JL, Arquizan C, Lamy C, et al. Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med 2001; 345:1740–1746.
Sacco RL, Prabhakaran S, Thompson JL, et al. Comparison of warfarin versus aspirin for the prevention of recurrent stroke or death: subgroup
analyses from theWarfarin-Aspirin Recurrent Stroke Study.Cerebrovasc Dis 2006; 22:4–12.
Halkes PH, van Gijn J, Kappelle LJ, et al. Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT):
a randomized controlled trial. Lancet Neurol 2007; 6:115–124.
Clinical trials. (2017). Available from: https://clinicaltrials.gov/ct2/show/ NCT02239120. Accessed 1 January 2017.
Clinical trials. (2017). Available from: https://clinicaltrials.gov/ct2/show/ NCT02313909. Accessed 1 January 2017.
Clinical trials. (2017). Available from: https://clinicaltrials.gov/ct2/show/ NCT02427126. Accessed 1 January 2017.
ดาวน์โหลด
เผยแพร่แล้ว
2019-02-13
รูปแบบการอ้างอิง
1.
เขียนดวงจันทร์ เ. Embolic Strokes of Undetermined Source. J Thai Stroke Soc [อินเทอร์เน็ต]. 13 กุมภาพันธ์ 2019 [อ้างถึง 31 ธันวาคม 2025];16(1):16-22. available at: https://he01.tci-thaijo.org/index.php/jtss/article/view/172085
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ข้อความภายในบทความที่ตีพิมพ์ในวารสารสมาคมโรคหลอดเลือดสมองไทยเล่มนี้ ตลอดจนความรับผิดชอบด้านเนื้อหาและการตรวจร่างบทความเป็นของผู้นิพนธ์ ไม่เกี่ยวข้องกับกองบรรณาธิการแต่อย่างใด การนำเนื้อหา ข้อความหรือข้อคิดเห็นของบทความไปเผยแพร่ ต้องได้รับอนุญาตจากกองบรรณาธิการอย่างเป็นลายลักษณ์อักษร ผลงานที่ได้รับการตีพิมพ์ในวารสารเล่มนี้ถือเป็นลิขสิทธิ์ของวารสาร
