Vascular contributions to cognitive impairment and dementia


  • Pornpatr Dharmasaroja Division of Neurology, Department of Medicine, Faculty of Medicine, Thammasat University, Pathumthani


stroke, dementia, vascular dementia, vascular risk factor


Vascular contributions to cognitive impairment and dementia is used to describe the role of a range of vascular risk and vascular lesions on cognition. Mid-life exposure (45-64 years) to hypertension, smoking, diabetes mellitus has greater impact on dementia risk than similar vascular risk factors in late-life (>65 years). The combined risk score is stronger predictor of cognitive decline than independent risk factors. After a stroke, approximate 30% of patients develop vascular dementia. Cognitive assessment should be performed at 3 months or beyond in those suspected cognitive decline, because early cognitive improvement has been found after acute stroke. For primary prevention, controlling some vascular risk factors during mid-life, such as hypertension has been shown to lower risk of mild cognitive impairment.


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How to Cite

Dharmasaroja P. Vascular contributions to cognitive impairment and dementia. J Thai Stroke Soc [Internet]. 2024 Apr. 10 [cited 2024 Jun. 24];23(1):14. Available from:



Review article