The effects of implementing preventive guidelines against ventilator-associated pneumonia in an isolation ward

Authors

  • Darunee Donratanapat Nakornping Hospital
  • Kamonwan Thaiwong Nakornping Hospital

Keywords:

ventilator-associated pneumonia, nursing practice guidelines, VAP prevention, incidence, VAP

Abstract

Introduction: Ventilator-associated pneumonia (VAP) is a significant hospital-acquired infection and a major cause of patient mortality. Nursing interventions play a crucial role in preventing VAP.

Objective: To investigate the incidence of VAP and to assess the adherence to and satisfaction with the implementation of VAP prevention guidelines

Methods: This quasi-experimental study compared outcomes before and after implementing VAP prevention guidelines in nurses at isolation ward and patients who admitted to the isolation ward 9/5 at Nakornping Hospital between September 17, 2023, and January 2024. Nurse adherence and satisfaction with the guidelines were also evaluated. Data were analyzed using Fisher’s exact probability test, independent t-test, and incidence rate ratio (IRR) to determine the incidence of VAP.

Results: Before implementation, 40 patients were included, 64.00% male, with an average age of 61.67 ± 18.08 years. After implementation, 40 patients were included, 60.00% male, with an average age of 66.67±19.50 years. The incidence of VAP decreased following guideline implementation but was not statistically significant, from 22.84 to 11.83 cases per 1,000 ventilator days (IRR 0.52, 95% CI = 0.12–1.86, p=0.282). Thirteen nurses participated in the implementation, with an average age of 30.69±7.16 years and an average work experience of 7.92±7.48 years. Of the 23 recommended practices, 17 (73.91%) were fully adhered to, while 21 (91.30%) achieved over 90% adherence. The least-followed practice was an assessing readiness for ventilator weaning (46.15%). Nurse satisfaction with the guidelines was rated as very high across all aspects, with an average satisfaction score of 4.71±0.31.

Conclusion: The VAP prevention guidelines in this study demonstrated a trend toward reducing VAP incidence, although statistical significance was not achieved. Further studies with a larger sample size and longer duration are recommended. Nevertheless, the observed clinical reduction in VAP incidence is relevant to patient outcomes and healthcare costs, supporting the continued use of these guidelines with long-term follow-up.

References

Healthcare-Associated Infections (HAIs). 2020 National and State Healthcare-Associated Infections Progress Report [Internet]. U.S.A.: Center for Disease Control and Prevention; c2021 [update 2021 Oct 26]. Available from: https://archive.cdc.gov/www_cdc_gov/hai/data/archive/2020-HAI-progress-report.html

Rosenthal VD, Al-Abdely HM, El-Kholy AA, AlKhawaja SAA, Leblebicioglu H, Mehta Y, et al. International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module. Am J Infect Control. 2016;44(12):1495-504. doi: 10.1016/j.ajic.2016.08.007.

Zhang TT, Tang SS, Fu LJ. The effectiveness of different concentrations of chlorhexidine for prevention of ventilator-associated pneumonia: a meta-analysis. J Clin Nurs. 2014;23(11-12):1461-75. doi: 10.1111/jocn.12312.

Ministry of Public Health, Department of Disease Control, Bamrasnaradura Infectious Diseases Institute. Situation of infection in hospital 2020-2022 [Internet]. Nonthaburi: Bamrasnaradura Infectious Diseases Institute; c2023 [update 2023 Aug 3]. Available from: https://nicc-ipcprogram.org/ [In Thai]

Nakornping Hospital. Annual report 2022. Chiangmai: Nakornping hospital; 2022. [In Thai]

Rosenthal VD, Chaparro GJ, Servolo-Medeiros EA, Souza-Fram D, Escudero DVDS, Gualtero-Trujillo SM, et al. An eight-year multicenter study on short-term peripheral intravenous catheter-related bloodstream infection rates in 100 intensive care units of 9 countries in Latin America: Argentina, Brazil, Colombia, Costa Rica, Dominican Republic, Ecuador, Mexico, Panama, and Venezuela. Findings of the International Nosocomial Infection Control Consortium (INICC). Infect Control Hosp Epidemiol. 2021;42(9):1098-104. doi: 10.1017/ice.2020.1373.

He Q, Wang W, Zhu S, Wang M, Kang Y, Zhang R, et al. The epidemiology and clinical outcomes of ventilator-associated events among 20,769 mechanically ventilated patients at intensive care units: an observational study. Crit Care. 2021;25(1):44. doi: 10.1186/s13054-021-03484-x.

Lertloykulchai T. The Incidence and Etiology of Hospital-acquired Pneumonia and Ventilator-associated Pneumonia in Somdetphraphutthaloetla Hospital. Chonburi Hospital Journal. 2021;46(2):121-30. [In Thai]

Forrester JD, Maggio PM, Tennakoon L. Cost of Health Care-Associated Infections in the United States. J Patient Saf. 2022;18(2):e477-9. doi: 10.1097/PTS.0000000000000845.

Kassimma T. Effectiveness of the ventilator-associated pneumonia prevention program among medical intensive care unit nurses [dissertation]. Chiang Mai: Chiang Mai University; 2023. [In Thai]

Xu Y, Lai C, Xu G, Meng W, Zhang J, Hou H, et al. Risk factors of ventilator-associated pneumonia in elderly patients receiving mechanical ventilation. Clin Interv Aging. 2019;14:1027-38. doi: 10.2147/CIA.S197146.

Othman HA, Gamil NM, Elgazzar AEM, Fouad TA. Ventilator associated pneumonia, incidence and risk factors in emergency intensive care unit Zagazig university hospitals. Egypt J Chest Dis Tuberc. 2017;66(4):703-8.

Seubniam S, Ruaisungnoen W, Saensom D. Factors Associated with Early-onset Ventilator-associated Pneumonia Development among Critically Ill Medical Patients. Journal of Nursing and Health Care. 2017;35(1):137-45. [In Thai]

Ministry of Public Health, Department of Disease Control, Bamrasnaradura Infectious Diseases Institute. Manual for prevention and control of infection in hospitals. Nonthaburi: Agricultural Cooperatives Association of Thailand Printing House; 2013. p. 44-48. [In Thai]

Infection Control Department nakornping Hospital. Evidence-based practice guidelines Ventilator-Associated Pneumonia–VAP [Internet]. Chiangmai: Nakornping Hospital; c2023 [update 2023 Jan 23]. Available from: https://mis.nkp-hospital.go.th/institute/admInstitute/nFile/sID2023-04-11_154447.pdf [In Thai]

Sornsomnuk S, Khuwatsamrit K, Monkong S. Effects of Using Nursing Practice Guidelines for Ventilator Associated Pneumonia Prevention on the Incidence of Ventilator Associated Pneumonia. Ramathibodi Nursing Journal. 2017;23(3):284-97. [In Thai]

Taopa S, Panuwet R. The effects development of nursing practice guidelines to prevent ventilator associated pneumonia (VAP) in Medical Intensive Care Unit, Nongbualamphu Hospital [Internet]; c2022 [update 2022 Aug 9]. Available from: https://r8way.moph.go.th/r8wayNewadmin/page/upload_file/20220908043820.pdf [In Thai]

Thamcharoentrakul B, Saensom B. Effects of Using Nursing Practice Guideline for Ventilator Associated Pneumonia Prevention: Medical Department. The Journal of Baromarajonani College of Nusing, Nakhonratchasima. 2019;25(1):25-42. [In Thai]

Mohamed KAE. Compliance with VAP bundle implementation and its effectiveness on surgical and medical sub-population in adult ICU. Egypt J Chest Dis Tuberc. 2014;63(1):9-14.

Ruangwattana S, Kaewkhumpa P, Thummapok O. The development of nursing supervision program model for the first-line manager based towards patient safety in the intensive care nursing department, Lamphun Hospital. Journal of Nakornping Hospital. 2024;15(1):108-24. [In Thai]

Kongkirdlap K, Unahalekhaka A, Kasatpibal N. Practices and Obstacles in Ventilator-Associated Pneumonia Prevention Among Registered Nurses in Medical Care Units. Nursing Journal. 2021;48(3):104-14. [In Thai]

Ruangkhae S, Unahalekhaka A, Kasatpibal N. Practices and Obstacles in Prevention of Ventilator-Associated Pneumonia Among Registered Nurses in Intensive Care Units. Nursing Journal. 2021;48(2):84-94. [In Thai]

Unahalekhaka A. Prevention of Ventilator-Associated Pneumonia. Chiang Mai: NUNTAPUN PRINTING; 2022. [In Thai]

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Published

03-07-2025

How to Cite

Donratanapat, D. ., & Thaiwong, K. . (2025). The effects of implementing preventive guidelines against ventilator-associated pneumonia in an isolation ward. Journal of Nakornping Hospital, 16(2), 271–284. retrieved from https://he01.tci-thaijo.org/index.php/jnkp/article/view/267148

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Section

Research article