Prevalence and associated factors of anxiety and depression among COVID-19 patients after treatment from the Chiang Mai Field Hospital

Authors

  • Patcharaporn Intawong Nakornping Hospital
  • Pongpreeda Saenchitta Suanprung Psychiatric Hospital
  • Rojanaphun Nandidarbha ์Nakornping Hospital
  • Chanchanok Aramrat Maharaj Nakorn Chiang Mai Hospital

Keywords:

COVID-19, prevalence, risk factor, anxiety, depression, field hospital

Abstract

Introduction: Nowadays, many countries have reported up to 1 in 3 prevalence of anxiety and depression in COVID-19 patients after treatment in large hospitals, but the prevalence of patients recovering from COVID-19 treatment in small hospitals is limited.

Objective: To explore the prevalence and associating factors of anxiety and depression among COVID-19 patients after treatment at the Chiang Mai field hospital.

Methods: This research was a cross-sectional study conducted during September to October 2021. Data collected included general information, patient’s medical history, patients’ concern about COVID-19. The Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) were used as indicators of symptoms of anxiety and depression to assess the mental health of the patient. The correlation between factors was analyzed with multivariate logistic regression statistics.

Results: A total of 375 patients participated in the study, 62% of patients were male. The mean age was 33.72 years (SD = 10.77). The study found the prevalence of anxiety and depression was 3.2% and 10.66%, respectively. Factors associated with depression were age (Adj. Odds ratio = 0.93, p-value = 0.010), patients with underlying diseases (27.2%, Adj. Odds ratio = 3.41, p-value = 0.011), patients with a history of psychiatric disorders (9.07%, Adj. Odds ratio = 9.16, p-value < 0.001 ) and all patients concerned about COVID-19 infection have a statistically significant with depression (Adj. Odds ratio = 6.32, p-value = 0.008). Factor associated with anxiety were patients living outside Chiang Mai province (2.4%, Adj. Odds ratio = 11.23, p-value = 0.028) and patients with a history of psychiatric disorders (9.07%, Adj. Odds ratio = 11.36, p-value = 0.002).

Conclusions: The prevalence of anxiety and depression was low in COVID-19 patients who had mild or no symptoms after being discharged from the Chiang Mai field hospital. This information can be used as a guideline for managing the mental health problems of COVID-19 patients in small field hospitals after discharge, especially those at risks.

References

Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-62. doi: 10.1016/S0140-6736(20)30566-3.

Liu S, Yang L, Zhang C, Xiang Y-T, Liu Z, Hu S, et al. Online mental health services in China during the COVID-19 outbreak. Lancet Psychiatry. 2020;7(4):e17-8. doi: 10.1016/S2215-0366(20)30077-8.

Zhang J, Wu W, Zhao X, Zhang W. Recommended psychological crisis intervention response to the 2019 novel coronavirus pneumonia outbreak in China: a model of West China Hospital. Precis Clin Med. 2020;3(1):3-8. doi: 10.1093/pcmedi/pbaa006.

Dai Y, Hu G, Xiong H, Qiu H, Yuan X. Psychological impact of the coronavirus disease 2019 (COVID-19) outbreak on healthcare workers in China. medRxiv. doi: https://doi.org/10.1101/2020.03.03.20030874.

Wang C, Pan R, Wan X, Tan Y, Xu L, Ho CS, et al. Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China. Int J Environ Res Public Health. 2020;17(5):1729. doi: 10.3390/ijerph17051729.

Kong X, Zheng K, Tang M, Kong F, Zhou J, Diao L, et al. Prevalence and Factors Associated with Depression and Anxiety of Hospitalized Patients with COVID-19. medRxiv. doi: https://doi.org/10.1101/2020.03.24.20043075

Saidi I, Koumeka PP, Ait Batahar S, Amro L. Factors associated with anxiety and depression among patients with Covid-19. Respir Med. 2021;186:106512. doi: 10.1016/j.rmed.2021.106512.

McWhinney IR. Teaching the principles of family medicine. Can Fam Physician. 1981;27:801-4.

Abulsaad AM, Sonbol HM, Elwasify MA, Elboraie OA. Anxiety and depression among COVID-19 survivors: a cross-sectional study. Middle East Curr Psychiatry. 2023;30(1):78. doi: https://doi.org/10.1186/s43045-023-00351-z

Nguyen HB, Nguyen THM, Vo THN, Vo TCN, Nguyen DNQ, Nguyen H-T, et al. Post-traumatic stress disorder, anxiety, depression and related factors among COVID-19 patients during the fourth wave of the pandemic in Vietnam. Int Health. 2023;15(4):365-75. doi: 10.1093/inthealth/ihac040.

Guillen-Burgos HF, Galvez-Florez JF, Moreno-Lopez S, Gonzalez I, Guillen M, Anaya JM. Factors associated with mental health outcomes after COVID-19: A 24-month follow-up longitudinal study. Gen Hosp Psychiatry. 2023;84:241-9.

Wang S, Quan L, Chavarro JE, Slopen N, Kubzansky LD, Koenen KC, et al. Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post-COVID-19 Conditions. JAMA Psychiatry. 2022;79(11):1081-91. doi: 10.1001/jamapsychiatry.2022.2640

Gad BK, Arafa MA, Attia AF, Farahat AH, Abdou MS. Depression, anxiety, and stress among COVID-19 patients in South Sinai, Egypt: prevalence and associated predictors. Sci Rep. 2023;13(1):19193. doi: 10.1038/s41598-023-45775-z.

Suwanbamrung C, Pongtalung P, Trang LTT, Phu DH, Nam TT. Levels and risk factors associated with depression, anxiety, and stress among COVID-19 infected adults after hospital discharge in a Southern Province of Thailand. Journal of Public Health and Development. 2023;21(1):72-89. [In Thai]

Dai Z, Xiao W, Wang H, Wu Y, Huang Y, Si M, et al. Influencing factors of anxiety and depression of discharged COVID-19 patients in Wuhan, China. PLoS One. 2022;17(11):e0276608. doi: 10.1371/journal.pone.0276608.

Jiwattanasuk N, Pannavoravat P, Sirikanchana P. The Holistic Well-being Concepts in Relation to Quality of Life. ABAC ODI JOURNAL Vision Action Outcome. 2022;10(1):28-41. [In Thai]

Cuijpers P, Vogelzangs N, Twisk J, Kleiboer A, Li J, Penninx BW. Comprehensive meta-analysis of excess mortality in depression in the general community versus patients with specific illnesses. Am J Psychiatry. 2014;171(4):453-62. doi: 10.1176/appi.ajp.2013.13030325.

Neuman BM, Young RJ. A model for teaching total person approach to patient problems. Nurs Res. 1972;21(3):264-9. doi: 10.1097/00006199-197205000-00015.

Saxton JW. How to increase economic returns and reduce liability exposure: Part 1--Patient satisfaction as an economic tool. J Med Pract Manage. 2001;17(3):142-4.

Dear BF, Titov N, Sunderland M, McMillan D, Anderson T, Lorian C, et al. Psychometric comparison of the generalized anxiety disorder scale-7 and the Penn State Worry Questionnaire for measuring response during treatment of generalised anxiety disorder. Cogn Behav Ther. 2011;40(3):216-27. doi: 10.1080/16506073.2011.582138.

Spitzer RL, Williams JB, Kroenke K. General Anxiety Disorder-7 [Internet]; 2015. Available from: https://www.beardenbehavioralhealth.com/wp-content/uploads/NP-NEW-PATIENT-FORM-ADULT-pdf.pdf

Lotrakul M, Sumrithe S, Saipanish R. Reliability and validity of the Thai version of the PHQ-9. BMC psychiatry. 2008;8:46. doi: 10.1186/1471-244X-8-46.

Zhou J, Liu L, Xue P, Yang X, Tang X. Mental health response to the COVID-19 outbreak in China. Am J Psychiatry. 2020;177(7):574-5. doi: 10.1176/appi.ajp.2020.20030304.

Badinlou F, Lundgren T, Jansson-Fröjmark M. Mental health outcomes following COVID-19 infection: impacts of post-COVID impairments and fatigue on depression, anxiety, and insomnia-a web survey in Sweden. BMC psychiatry. 2022;22(1):743. doi: 10.1186/s12888-022-04405-0.

Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2021;397(10270):220-32. doi: 10.1016/S0140-6736(20)32656-8..

Klaser K, Thompson EJ, Nguyen LH, Sudre CH, Antonelli M, Murray B, et al. Anxiety and depression symptoms after COVID-19 infection: results from the COVID Symptom Study app. J Neurol Neurosurg Psychiatry. 2021;92(12):1254-8. doi: 10.1136/jnnp-2021-327565.

Mazza MG, Palladini M, Poletti S, Benedetti F. Post-COVID-19 depressive symptoms: Epidemiology, pathophysiology, and pharmacological treatment. CNS drugs. 2022;36(7):681-702. doi: 10.1007/s40263-022-00931-3.

Saenchitta P, Prompantakorn P, Mahathep P. Investigation on the Prevalence of Anxiety and Depression among COVID-19 Patients in the Chiang Mai Field Hospital. Journal of Nakornping Hospital. 2022;13(1):2-16. [In Thai]

Fitzgerald PJ. Serious infection may systemically increase noradrenergic signaling and produce psychological effects. Med Hypotheses. 2020;139:109692. doi: 10.1016/j.mehy.2020.109692.

Kroenke K, Spitzer RL, Williams JB, Monahan PO, Löwe B. Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection. Ann Intern Med. 2007;146(5):317-25. doi: 10.7326/0003-4819-146-5-200703060-00004.

Kroenke K, Spitzer RL, Williams JB. The Patient Health Questionnaire-2: validity of a two-item depression screener. Med Care. 2003;41(11):1284-92. doi: 10.1097/01.MLR.0000093487.78664.3C.

Wang Y, Kala MP, Jafar TH. Factors associated with psychological distress during the coronavirus disease 2019 (COVID-19) pandemic on the predominantly general population: A systematic review and meta-analysis. PLoS One. 2020;15(12):e0244630. doi: 10.1371/journal.pone.0244630.

Xiao X, Yang X, Zheng W, Wang B, Fu L, Luo D, et al. Depression, anxiety and post-traumatic growth among COVID-19 survivors six-month after discharge. Eur J Psychotraumatol. 2022;13(1):2055294. doi: 10.1080/20008198.2022.2055294.

Fukase Y, Ichikura K, Murase H, Tagaya H. Depression, risk factors, and coping strategies in the context of social dislocations resulting from the second wave of COVID-19 in Japan. BMC Psychiatry. 2021;21(1):33. doi: 10.1186/s12888-021-03047-y.

Salari N, Hosseinian-Far A, Jalali R, Vaisi-Raygani A, Rasoulpoor S, Mohammadi M, et al. Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis. Global Health. 2020;16(1):57. doi: 10.1186/s12992-020-00589-w.

Re’em Y, Stelson EA, Davis HE, McCorkell L, Wei H, Assaf G, et al. Factors associated with psychiatric outcomes and coping in Long COVID. Nature Mental Health. 2023;1:361-72. doi: https://doi.org/10.1038/s44220-023-00064-6

Deng J, Zhou F, Hou W, Silver Z, Wong CY, Chang O, et al. The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: a meta-analysis. Ann N Y Acad Sci. 2021;1486(1):90-111. doi: 10.1111/nyas.14506.

Sayeed A, Kundu S, Al Banna MH, Christopher E, Hasan MT, Begum MR, et al. Mental health outcomes of adults with comorbidity and chronic diseases during the COVID-19 pandemic: a matched case-control study. Psychiatr Danub. 2020;32(3-4):491-8. doi: 10.24869/psyd.2020.491.

Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. lancet. 2020;395(10223):507-13. doi: 10.1016/S0140-6736(20)30211-7.

Hazumi M, Usuda K, Okazaki E, Kataoka M, Nishi D. Differences in the course of depression and anxiety after COVID-19 infection between recovered patients with and without a psychiatric history: A cross-sectional study. Int J Environ Res Public Health. 2022;19(18):11316. doi: 10.3390/ijerph191811316.

Heiberg KE, Heggestad AKT, Jøranson N, Lausund H, Breievne G, Myrstad M, et al. 'Brain fog', guilt, and gratitude: Experiences of symptoms and life changes in older survivors 6 months after hospitalisation for COVID-19. Eur Geriatr Med. 2022;13(3):695-703. doi: 10.1007/s41999-022-00630-8.

Jatic Z, Trifunovic N, Erkocevic H, Hasanovic E, Ceric K, Bajrami B, et al. Family Medicine Practice During COVID-19 Pandemic in Canton Sarajevo: Positive and Negative Aspects. Mater Sociomed. 2022;34(1):44-9. oi: 10.5455/msm.2022.33.44-49.

National Institute for Health and Care Excellence (NICE). COVID 19 Rapid Guideline: managing COVID-19 [Internet]. London: NICE; 2021 [updated 2023 Nov 30] Available from: https://www.nice.org.uk/guidance/ng191

Downloads

Published

29-12-2023

How to Cite

Intawong, P., Saenchitta, P., Nandidarbha, R., & Aramrat, C. (2023). Prevalence and associated factors of anxiety and depression among COVID-19 patients after treatment from the Chiang Mai Field Hospital. Journal of Nakornping Hospital, 14(2), 374–393. Retrieved from https://he01.tci-thaijo.org/index.php/jnkp/article/view/265912

Issue

Section

Research article