Factors Related to Severity of Symptoms of Patients Infected with Coronavirus Disease 2019 in the Manchakiri District Khon Kaen Province

Abstract

          This analytical research was a retrospective case-control study. The objective of this study was to investigate the factors related to the severity of symptoms and the characteristics of patients infected with coronavirus disease 2019 treated as inpatients at Manchakiri Hospital, Khon Kaen Province. The data collection period was from April 2020 – April 2022. A total of 508 patients were investigated, divided into an experimental group (n=254) and a control group (n=254). Data was collected using a medical record form.

         The statistics used were descriptive and inferential statistics, using multiple logistic regression to describe the relationship between variables.

           The results indicated that the factors associated with the severity of symptoms in patients with coronavirus disease 2019 included patients over 60 years of age (OR_adj = 6.45, 95%CI: 2.29-18.16, p-value <0.001), BMI increased by 1 kg/m² (95%CI: 1.07-1.20, p-value = <0.001), unvaccinated patients (OR_adj = 3.79 , 95%CI: 1.08-13.27, p-value = 0.037), patients with cough (OR_adj = 1.09,95%CI: 1.20-3.02, p-value = 0.006), Patients with an increase in respiratory rate by one unit (OR_adj = 1.43,95%CI: 1.13-1.80, p-value = 0.003).

          From the results of the research, it was found that knowing the factors related to the severity of the patient’s condition could be used to develop a guideline for patient care including knowledge on preventing risk factors to effectively reduce the likelihood of the coronavirus disease 2019 outbreak in the community.