Effect of a Cholangiocarcinoma Preventive Behavior Development Program for Risk Group at Banyangbor-e Tambon Health Promoting Hospital, Surin Province

Abstract

The objectives of this quasi-experimental research were to compare the cholangiocarcinoma (CCA) preventive behaviors before and after the experiment of an experimental group and a comparison group, and after the experiment between the experimental group and the comparison group, and to compare the Opisthorchis viverini (OV) infection rate after the experiment of the experimental group and the comparison group. The samples comprised 59 people at risk of developing CCA, aged 35-60 years old with periductal fibrosis (PDF) at moderate and severe level. They were selected by the purposive sampling technique as they met the inclusion criteria. Twenty nine samples were selected from Banyangbor-e Tambon Health Promoting Hospital as an experimental group and 30 samples were selected from Nongreoa Tambon Health Promoting Hospital as the comparison group, respectively. All of them were similar in age and PDF level. The experimental tool was the CCA preventive behavior development program based on PRECEDE-PROCEED model. The data collecting tool was a questionnaire with 4 parts: (1) general data, (2) CCA preventive behaviors with content validity index 0.96 and Cronbach’s alpha coefficient 0.79, and (3) result of OV examination. Data were analyzed by descriptive statistics, t-test, Wilcoxon matched pairs signed rank test and Z test for proportion. The results found as follows. After the experiment, nutritional, exercise and overall CCA preventive behavior of the experimental group and the comparison group were significantly higher than before the experiment (p-value < .05). After the experiment, nutritional behavior of the experimental group were significantly higher than that of the comparison group (p-value < .05), and exercise and overall CCA preventive behavior were significantly increased more than the comparison group (p-value < .05); and (2) after the experiment, the OV infection rate of the experimental group was not significantly different from the comparison group (p-value > .05).