The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane

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Natthakun Charanthanyakun
Kathawut Tachasuttirut
Piyanuj Permpanich
Sahatut Kaewkumnert
Warit Powcharoen

Abstract

Objective: To evaluate the effect of heat-compression to platelet-rich fibrin (PRF) membrane in degradation time, weight loss and to examine surface fibrin structure using scanning electron microscope (SEM).


Methods: Sixty PRF membranes that were prepared from human blood (ten healthy volunteers). Samples were compressed at various temperatures and were arranged into six groups: control (room temperature), 60, 70, 80, 90 and 100°C. Nine of the ten samples from each group were evaluated for their degradation time and weight loss. One remaining sample was examined the surface fibrin structure using SEM.


Results: The 90 and 100°C groups had significantly different degradation times compared to those in the control, 60 and 70°C groups (p<0.05). There was no significant difference in the mean weight percentage among the six groups on each day (p<0.05). But when compared among the days in the same group, the 90 and 100°C groups were significantly different in the early phase to 11 and 6 days, respectively. The surface fibrin structure in the 90 and 100°C groups showed the least interfibrous space and lowest porosity.


Conclusion: The 90 and 100°C groups had significantly longer degradation times and delayed the early stage of degradation. It might be applied in surgical operations that need PRF membrane stability in the early phase.

Article Details

How to Cite
Charanthanyakun, N. ., Tachasuttirut , K. ., Permpanich, P. ., Kaewkumnert, S. ., & Powcharoen, W. . (2020). The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane. Chiang Mai Dental Journal, 41(2), 75–87. Retrieved from https://he01.tci-thaijo.org/index.php/cmdj/article/view/243988
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Original article

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