Angina Bullosa Haemorrhagica
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Abstract
Angina bullosa haemorrhagica (ABH) is a rare and benign disorder, localized in oral mucosa as blood-filled bullae, which is not attributable to blood dyscrasia and autoimmune vesiculobullous disorders. The diagnosis of ABH should be based on clinical features, medical history, histopathologic and immunopathologic features. The blood-filled bullae can heal spontaneously without scarring, if necessary, symptomatic treatments should be done. This article reviews the etiology, pathogenesis, clinical features, diagnosis and management of ABH.
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References
Badham NJ. Blood blisters and the oesophageal cast. J Laryngol Otol 1967; 81(7): 791-803.
Scully C. The oral cavity. In: Rook AJ. Wilkinson DS, Ebling FJG. Eds. Textbook of Dermatology 1992; Blackwell Scientific Publications: Oxford. pp. 2732-2733.
Deblauwe BM, van der Waal I. Blood blisters of the oral mucosa (angina bullosa haemorrhagica). J Am Acad Dermatol 1994; 31:341-344.
Horie N, Kawano R, Inaba J, et al. Angina bullosa hemorrhagica of the soft palate: a clinical study of 16 cases. J Oral Sci 2008; 50(1): 33-36.
Giuliani M, Favia GF, Lajolo C, Miani CM. Angina bullosa haemorrhagica: presentation of eight new cases and a review of the literature. Oral Dis 2002; 8(1): 54-58.
Beguerie JR, Gonzalez S. Angina bullosa hemorrhagica: report of 11 cases. Dermatol Reports 2014; 6(1): 5282.
Shoor H, Mutalik S, Pai KM. Angina bullosa haemorrhagica. BMJ Case Rep 2013; 2013.
Hopkins R, Walker DM. Oral blood blisters: angina bullosa haemorrhagica. Br J Oral Maxillofac Surg 1985; 23(1): 9-16.
Stephenson P, Lamey PJ, Scully C, Prime SS. Angina bullosa haemorrhagica: clinical and laboratory features in 30 patients. Oral Surg Oral Med Oral Pathol 1987; 63(5): 560-565.
de las Heras ME, Moreno R, Nunez M, Gomez MI, Ledo A. Angina bullosa hemorrhagica. J Dermatol 1996; 23(7): 507-509.
Singh D, Misra N, Agrawal S, Misra P. Angina bullosa haemorrhagica. BMJ Case Rep 2013; 2013.
Paci K, Varman KM, Sayed CJ. Hemorrhagic bullae of the oral mucosa. JAAD Case Rep 2016; 2(6): 433-435.
Edwards S, Wilkinson JD, Wojnarowska F. Angina bullosa haemorrhagica--a report of three cases and review of the literature. Clin Exp Dermatol 1990; 15(6): 422-424.
Poskitt L. Angina bullosa haemorrhagica: associated steroid inhaler use. N Z Med J 1991; 104(925): 522.
Higgins EM, du Vivier AW. Angina bullosa haemorrhagica--a possible relation to steroid inhalers. Clin Exp Dermatol 1991; 16(4): 244-246.
Corson MA, Sloan P. Angina bullosa haemorrhagica: an unusual complication following crown preparation. Br Dent J 1996; 180(1): 24-25.
Gomez RS, Pelka M, Johannessen AC, Hornstein OP, von den Driesch P. CD36 (OKM5) antigen expression on human mucosal epithelia is associated with keratinization type. J Dermatol 1997; 24(7): 435-440.
Grinspan D, Abulafia J, Lanfranchi H. Angina bullosa hemorrhagica. Int J Dermatol 1999; 38(7): 525-528.
High AS, Main DM. 'Angina bullosa haemorrhagica: a complication of long-term steroid inhaler use'. Br Dent J 1988; 165(10): 357.
Garlick JA, Calderon S. Oral blood blisters in angina bullosa haemorrhagica secondary to trauma of eating and dental injection. Br Dent J 1988; 165(8): 286-287.
Toogood JH, Jennings B, Greenway RW, Chuang L. Candidiasis and dysphonia complicating beclomethasone treatment of asthma. J Allergy Clin Immunol 1980; 65(2): 145-153.
Yamamoto K, Fujimoto M, Inoue M, Maeda M, Yamakawa N, Kirita T. Angina bullosa hemorrhagica of the soft palate: report of 11 cases and literature review. J Oral Maxillofac Surg 2006; 64(9): 1433-1436.
Pahl C, Yarrow S, Steventon N, Saeed NR, Dyar O. Angina bullosa haemorrhagica presenting as acute upper airway obstruction. Br J Anaesth 2004; 92(2): 283-286.
Curran AE, Rives RW. Angina bullosa hemorrhagica: an unusual problem following periodontal therapy. J Periodontol 2000; 71(11): 1770-1773.
Hosain SI, Bounds G, Stanford J. Angina haemorrhagica bullosa causing respiratory obstruction postoperatively. Anaesthesia 1991; 46(5): 422.
Stephenson P, Scully C, Prime SS, Daly HM. Angina bullosa haemorrhagica: lesional immunostaining and haematological findings. Br J Oral Maxillofac Surg 1987; 25(6): 488-491.
Daly CG. Blood blisters on the soft palate in angina bullosa haemorrhagica. Case reports. Aust Dent J 1988; 33(5): 400-403.
Korman N. Bullous pemphigoid. J Am Acad Dermatol 1987; 16(5 Pt 1): 907-924.
Dominguez JD, Rodriguez-Peralto JL, Iglesias L. Recurrent oral blood blisters. Arch Dermatol 1999; 135(5): 593-594, 596-597.
Guillot B. Skin reactions to inhaled corticosteroids. Clinical aspects, incidence, avoidance, and management. Am J Clin Dermatol 2000; 1(2): 107-111.
Pongsiriwet S, Sangkaew P. Mucous membrane pemphigoid: A review of literature. CM Dent J 2018; 39(1): 25-42. (in Thai)
Forman L, Nally FF. Oral non-dystrophic bullous eruption mainly limited to the gingivae: a mechano bullous response. A variant of cicatricial mucous membrane pemphigoid? Br J Dermatol 1977; 96(2): 111-117.
Goncalves LM, Bezerra Junior JR, Cruz MC. Clinical evaluation of oral lesions associated with dermatologic diseases. An Bras Dermatol 2010; 85(2): 150-156.
Schwartz HC, Olson DJ. Amyloidosis: a rational approach to diagnosis by intraoral biopsy. Oral Surg Oral Med Oral Pathol 1975; 39(6): 837-843.
Gammon WR, Briggaman RA, Woodley DT, Heald PW, Wheeler CE, Jr. Epidermolysis bullosa acquisita--a pemphigoid-like disease. J Am Acad Dermatol 1984; 11: 820-832.
Northover JM, Pickard JD, Murray-Lyon IM, Presbury DG, Haskell R, Keith DA. Bullous lesions of the skin and mucous membranes in primary amyloidosis. Postgrad Med J 1972; 48(560): 351-353.