Application of monoclonal antibody in medicine

Abstract

Since, 1975 when monoclonal antibody is succeed by using mouse monoclonal hybridoma technique until right now; monoclonal antibody production technique is continuously developed and monoclonal antibody is applied to use with many fields of medicine and science such as blood bank, pharmacognosy and therapeutic antibody. In field of blood bank, monoclonal antibody is used for produce blood group reagent. Also, in field of pharmacognosy, monoclonal antibody and single chain variable fragments (scFvs) are used for analysis of quantitative and qualitative of herb and traditional medicine. In addition, monoclonal antibody is used for diagnostic of tumor marker and used for antibody therapy in cancer patient. Monoclonal antibody is very useful. Therefore, this review article aimed to present history and evaluation of monoclonal antibody production technique from past to present. Also, this article discussed benefits and how to apply monoclonal antibody with many fields of medicine and science with safe and gain the most benefits.