Biochemical bone marker in percentage for assessment of bisphosphonates in osteoporosis treatment

Abstract

Bone mineral density (BMD) test focuses on increased or decreased bone density, but biochemical bone marker (BMK) blood test can help evaluate bone quality, balance of bone resorption, bone formation rate, and bone life cycle. Besides BMK can help adjust the dose of bisphosphonate by turning the results in percentage. Since BMK blood test did not firstly implement, it has been generally assessed whether the bone resorption and the bone formation are increased and decreased at the same time or note. This method of balancing BMK into percentage was firstly initiated in my research, published in 2011. The balance of bone resorption and bone formation should not be ± 10% significantly different. It can be said that BMK value adjustment in percentage has greatly contributed to drug adjustment accuracy or planning. The research on this topic has been honored in the top 20 papers on Osteoporosis in 2011.