Hepatitis A

Authors

  • Sunida Vandelaer Department of Microbiology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society

Keywords:

Hepatitis A virus, laboratory diagnosis

Abstract

Hepatitis A, a liver injury caused by hepatitis A virus (HAV) infection, is one of a major global public-health problems that are enterically transmitted. It is estimated that 1.5 million people with hepatitis A virus (HAV) infections worldwide. The transmission of HAV occurs mainly by the fecal-oral route. There are six major genotypes of HAV but only one serotype. HAV genotypes 1, 2 and 3 are mainly restricted to humans whereas genotypes 4, 5 and 6 cause simian infections. The common laboratory testing for HAV infection included detection of IgM and IgG anti-HAV antibodies, detection of HAV RNA and HAV antigen. This article reviews the
information on basic knowledge of HAV, epidemiology, transmissions, pathogenesis, preventions and the laboratory diagnosis of HAV infection.

Downloads

Published

2019-01-22

Issue

Section

Review article