อัลตราซาวด์ร่วมกับการกระตุ้นเส้นประสาทเปรียบเทียบกับอัลตราซาวด์โฟโนโฟเรซิส ด้วยยาไพร็อคซิแคมในภาวะปวดเข่าจากข้อเข่าเสื่อม: การศึกษาทดลองชนิดเปรียบเทียบ โดยวิธีสุ่มและมีการปกปิด

อัลตราซาวด์ร่วมกับการกระตุ้นเส้นประสาทเปรียบเทียบกับอัลตราซาวด์โฟโนโฟเรซิส ด้วยยาไพร็อคซิแคมในภาวะปวดเข่าจากข้อเข่าเสื่อม: การศึกษาทดลองชนิดเปรียบเทียบ โดยวิธีสุ่มและมีการปกปิด

Authors

  • จริยา บุญหงษ์ Department of Rehabilitation Medicine, Faculty of Medicine, Chulalongkorn University
  • พิษณุ สุนทรปิยะพันธ์
  • อาภัชนีย์ พิริยะจารุกุล

Keywords:

knee osteoarthritis, pain, phonophoresis, transcutaneous electrical nerve stimulation

Abstract

Objective: Aims to compare effects of ultrasound combined transcutaneous electrical nerve stimulation (UltraTENS) and phonophoresis (PhP) in mild- to moderate degree of symptomatic knee OA.

Study design: A randomized double-blind, controlled comparative study.

Setting: Department of Rehabilitation Medicine, Faculty of Medicine, Chulalongkorn University

Subjects: Sixty-one patients (55 women and 6 men), ages 51 to 80 years (mean = 63.4±8.1), visual analog scale (VAS) of knee pain intensity ranged from 50-90 mm (mean=66.1) and Kellgren-Lawrence score of grade I-III, were randomly allocated into the Ultra TENs group and the PhP groups (n=31 and 30, respectively).

Method: The UltraTENS group received a combined ultrasound with TENS and a non-drug gel, whereas the PhP group received an ultrasound with piroxicam gel and sham TENS. All patients were treated for a total of 10 sessions, consisting of fi ve times per week and 10 min per session.

Outcome Measures: Using a double blinded procedure, the primary outcome measure was evaluated pre- and post- treatment using a 100-mm VAS. The secondary outcome was assessed using the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index.

Results: The UltraTENS and the PhP groups (p<0.001) experienced considerable improvement in both VAS and total WOMAC the WOMAC scores, but these fi ndings were not statistically signify cant (p=0.70 and 0.61, respectively).

Conclusion: Results show that UltraTENS and PhP were effective for relieving pain and improve functionality in Kellgren-Lawrence grades I-III knee OA. There were no signifi cant differences between groups. Both agents are recommended as effective combination methods for symptomatic knee OA treatment.

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Published

2017-08-29