Prevalence and associated factors of urine methamphetamine positive in maternal labor pain at delivery room of Phangnga hospital

Abstract

The purpose of this research was to study the prevalence and factors associated with urine methamphetamine positivity among pregnant women in labor and to compare maternal and neonatal outcomes between methamphetamine-positive and negative groups.               This retrospective cohort study analyzed data from pregnant women who presented at the labor room at Phannga Hospital between 1 October 2019 and 1 October 2023. Medical chart reviews tracked patients with urine methamphetamine tests. Demographics, history of prenatal care   substance use history, clinical manifestations, and clinical outcomes of both mothers and newborns were compared between urine methamphetamine-positive and negative groups. Comparisons were made using the Mann-Whitney U test and Fisher's exact test.

          The results reveled that the prevalence of urine methamphetamine-positive was 28 per 1,000 labor cases. Among 190 pregnant women tested, 91 were urine methamphetamine positive and 99 were negative. Median age was 28 years. The positive group had later initiation of antenatal care GA 22 weeks, history of no antenatal care 41.8%, multipara, exhibited more mood abnormalities 30%, birth before arrival 18.7%, history of substance used 98%, associated factors such as smoker drinker cannabis-kratom used 85.7 %, family members use drugs 67%. The positive group longer hospital stays for both newborns and mothers 4 days than negative group.

          Conclusion: The prevalence of methamphetamine used is on rise. Associated factors with detection include no antenatal care, multipara, abnormal behavior and emotions, birth before arrival, substances use, family members using substances.