COVID vaccine the hope of ending the outbreak

Main Article Content

Suppamas Punchuey

Abstract

By the end of year 2019, All over the world have known new diseases that had begun to spread from Wuhan city of China and become global pandemic affecting.  World Health Organization (WHO) had declared COVID-19 as a global health emergency on January 30, 2020 and characterized it pandemic on 11 March 2020. Within 14 months after the first case have reported in Wuhan The coronavirus COVID-19 is spread across 219 countries and territories affecting more than 126 million people worldwide and resulted in about 2.77 million deaths (~ 3% mortality rate)1. Needless to say, COVID-19 has become the most serious public health crisis of our generation and has a profound impact on the global economy and geopolitics


 Many drugs were invented and many measures for disease control had failed to stop the outbreak. Considering the rapid spread and high mortality of COVID-19, an effective vaccine is urgently needed and hoped to control this pandemic. Many researchers all over the world were race against time to develop the most efficiency vaccine against COVID-19 in the shortest times. To date the development of a new vaccine has been a long process that typically takes anywhere from 10 to 15 years. Hence, it is clearly a challenge to develop a vaccine against COVID-19 in a span of 12–24 months. Many of the vaccine platforms that complete phase 3 trial had announced their result of estimated vaccine efficacy above 70% and demonstration the safety efficacy to get approval. 


Although the demand for a vaccine far surpasses the production capacity, it will be beneficial to have a limited number of vaccines available for the more vulnerable population by the end of 2020 and for the rest of the global population by the end of 2021.

Article Details

How to Cite
1.
Punchuey S. COVID vaccine the hope of ending the outbreak. Kb. Med. J. [Internet]. 2022 Jan. 31 [cited 2024 May 22];4(1):63-81. Available from: https://he01.tci-thaijo.org/index.php/KBJ/article/view/254423
Section
Review Article

References

Worldometer. COVID-19 Coronavirus Pandemic [online]. 2021 Mar 27 [cited 2021 Mar 27]; Available from: URL: https://www.worldometers.info/coronavirus/

Kajal Rawat, Puja Kumari. COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies. Eur J Pharmacol [10.1016/j.ejphar.2020.173751] 2021 Feb 5 [cited2021 Jan 27]; 892: 173751. [8 Screens]. Available from: URL: https://www.sciencedirect.com/science/article/pii/S0014299920308438?via%3Dihub

World Health Organization. WHO Coronavirus Disease (COVID-19) Dashboard [online]. 2021 Mar 27 [cited 2021 Mar 27]; Available from: URL: https://covid19.who.int/

Omna Sharma1, Ali A. Sultan. A Review of the Progress and Challenges of Developing a Vaccine for COVID-19. Front. Immunol. [https://doi.org/10.3389/fimmu.2020.585354] 2020 Oct 14 [cited2021 Jan 27]. Available from: URL: https://www.frontiersin.org/articles/10.3389/fimmu.2020.585354/full

ยง ภู่วรวรรณ. โควิด -19 วัคซีน. วารสารกุมารเวชศาสตร์ 2563;59(4) : 245-247.

สมาคมโรคติดเชื้อในเด็กแห่งประเทศไทย, สมาคมโรคติดเชื้อแห่งประเทศไทย, กรมควบคุมโรค กระทรวงสาธารณสุข. วัคซีนโควิด-19 ท่านพร้อมหรือยัง [online]. 2021 Fab 4 [cited 2021 Fab 4]; Available from: URL: https://www.pidst.or.th/A985.html

วิกิพีเดีย สารานุกรมเสรี. ไวรัสโคโรนา [online]. 2021 Jan 27 [cited 2021 Jan 27]; Available from: URL: https://th.wikipedia.org/wiki/%E0%B9%84%E0%B8%A7%E0%B8%A3%E0%B8%B1%E0%B8%AA%E0%B9%82%E0%B8%84%E0%B9%82%E0%B8%A3%E0%B8%99%E0%B8%B2

สุรัชยา หมานมานะ, โสภณ เอี่ยมศิริถาวร, สุมนมาลย์ อุทยมกุล. โรคติดเชื้อไวรัสโคโรนา 2019 ( COVID-19). วารสารสถาบันบำราศนราดูร 2563; 14(2): 124-33.

กรมควบคุมโรค. แนวทางการให้วัคซีนโควิด 19 ในสถานการณ์การระบาดปี 64 ของประเทศไทย. 2021 Mar 27 [cited 2021 Mar 27]; Available from: URL: https://ddc.moph.go.th/uploads/files/1729520210301021023.pdf

Yen-Der Li, Wei-Yu Chi. Coronavirus vaccine development: from SARS and MERS to COVID-19. J Biomed Sci. [10.1186/s12929-020-00695-2] 2020 Dec 20 [cited2021 Jan 27]; 27: 104. [4 Screens]. Available from: URL: https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-020-00695-2

Carl Zimmer, Jonathan Corum. Coronavirus Vaccine Tracker. The New York Times 2021 Jan 26 [online]. 2021 Jan 27 [cited 2021 Jan 27]; Available from: URL: https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html

Yanjun Zhang, Gang Zeng. Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years:a randomised, double-blind, placebo-controlled,phase 1/2 clinical trial. Lancet Infect Dis. [https://doi.org/10.1016/S1473-3099(20)30843-4] 2021 Fab 1 [cited2021 Jan 27]; 21(2): 181-192. [6 Screens]. Available from: URL: https://www.thelancet.com/article/S1473-3099(20)30843-4/fulltext

Merryn Voysey, Sue Ann Costa Clemens. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet Infect Dis. [https://doi.org/10.1016/S0140-6736(20)32661-1] 2021 Jan 9 [cited2021 Jan 27]; 397: 99-111. [6 Screens]. Available from: URL: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32661-1/fulltext

ยง ภู่วรวรรณ. นพ.ยง ภู่วรวรรณ การแพทย์และสุขภาพ [online]. 2021 Jan 28 [cited 2021 Jan 28]; Available from: URL: https://www.facebook.com/%E0%B8%99%E0%B8%9E%E0%B8%A2%E0%B8%87-%E0%B8%A0%E0%B8%B9%E0%B9%88%E0%B8%A7%E0%B8%A3%E0%B8%A7%E0%B8%A3%E0%B8%A3%E0%B8%93-108692177438990/

Lindsey R. Baden, Hana M. El Sahly. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. The New England Journal of Medicine. [10.1056/NEJMoa2035389] 2020 Dec30 [cited2021 Jan 27]. Available from: URL: https://www.nejm.org/doi/full/10.1056/NEJMoa2035389

Fernando P. Polack, Stephen J. Thomas. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. The New England Journal of Medicine. [10.1056/NEJMoa2034577] 2020 Dec31 [cited2021 Jan 27]; 383:2603-2615 . [8 Screens]. Available from: URL: https://www.nejm.org/doi/full/10.1056/NEJMoa2034577?query=recirc_mostViewed_railB_article

รวงผึ้ง สุทเธนทร์. วัคซีนโควิด-19: เลือกชนิดใดดี [online]. 2021 Jan 12 [cited 2021 Jan 27]; Available from: URL: https://www.si.mahidol.ac.th/th/healthdetail.asp?aid=1451&fbclid=IwAR3b2bDu_97vg3ebetsZkwto52jUzqOXE9CxL1h_-ZIQXaFhvyCYHzp9AyI

World Health Organization. COVAX Announces new agreement, plans for first deliveries [online]. 2021 Feb 20 [cited 2021 Feb 20]; Available from: URL: https://www.who.int/news/item/22-01-2021-covax-announces-new-agreement-plans-for-first-deliveries

Our world in data. Statistics and Research Coronavirus (COVID-19) Vaccinations [online]. 2021 Jan 28 [cited 2021 Jan 28]; Available from: URL: https://ourworldindata.org/covid-vaccinations