Neuroleptic Malignant Syndrome

Main Article Content

Pornpirun Leeyangyuen

Abstract

We report a case of Neuroleptic malignant syndrome in 25-year old man. He was diagnosed substance induced psychosis  and controlled by antipsychotic drugs. This admission he had developed alteration of consciousness.  By his medication history, clinical symptoms, autonomic instability signs and investigation, Neuroleptic Malignant Syndrome was diagnosed in this patient.  It was essentially a diagnosis of exclusion, and treatment was mainly supportive in form of withdrawal of the neuroleptic medication (haloperidol, fluphenazine and chlorpromazine) and administration of bromocriptine. Although, relatively uncommon, NMS can be fatal.

Article Details

How to Cite
1.
Leeyangyuen P. Neuroleptic Malignant Syndrome . Kb. Med. J. [Internet]. 2022 Jan. 31 [cited 2024 Apr. 16];4(1):57-61. Available from: https://he01.tci-thaijo.org/index.php/KBJ/article/view/254422
Section
Case Report

References

Shalev A, Hermesh H, Munitz H. Mortality from neuroleptic malignant syndrome. J Clin Psychiatry 1989; 50:18.

Modi S, Dharaiya D, Schultz L, Varelas P. Neuroleptic Malignant Syndrome: Complications, Outcomes, and Mortality. Neurocrit Care 2016; 24:97.

Chandran GJ, Mikler JR, Keegan DL. Neuroleptic malignant syndrome: case report and discussion. CMAJ 2003; 169:439.

Strawn JR, Keck PE Jr, Caroff SN. Neuroleptic malignant syndrome. Am J Psychiatry 2007; 164:870.

Seitz DP, Gill SS. Neuroleptic malignant syndrome complicating antipsychotic treatment of delirium or agitation in medical and surgical patients: case reports and a review of the literature. Psychosomatics 2009; 50:8.

Adnet P, Lestavel P, Krivosic-Horber R. Neuroleptic malignant syndrome. Br J Anaesth. 2000;85:129–35.