Factors affecting Mortality in Patients with COVID-19: After the Declaration of an Endemic Disease

Authors

  • Orawan Bootthumpan Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Kingkarn Klinungkab Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Varanporn Panasittivana Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Tiwaporn Donthong Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
  • Wasana Lavin Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine, Ramathibodi Hospital, Mahidol University

Keywords:

Mortality, COVID-19, Endemic Disease

Abstract

Covid-19 problem It is a health problem that can cause from mild severity to death. This study used a retrospective study design in the intensive care unit from October 1, 2022, to June 30, 2023. The 54 subjects were collected using a general information questionnaire, Information on illness. This research used the descriptive including frequency, percentage, mean, and standard deviation and the Fisher’s exact test and chisquare test to analyze the factors affecting with mortality in patients with COVID-19.
The results revealed that 2 persons were dead. The sample groups were Charlson comorbidity index (CCI) ≥4 points (p-value = .025), Creatinine ≥1.73 (p-value = .031) were associated with mortality in patients with COVID-19 .The results of this research were information on treatment, monitoring and planning for future care.

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References

World Health Organization. Weekly epidemiological update COVID-19. 1. World Health Organization; 2023.

Lavin W, Yooyadmak P, & Phenglai C. Risk of mortality among COVID-19 patients admitted to intermediate ICU: A study during the third wave of COVID-19 pandemic. Journal of Disease Control. 2023;49(1):711-21. (in Thai)

Department of Disease Control. Situation Patients’ COVID 19 in Thailand. (Nonthaburi): Ministry of Public Health; 2023. (in Thai)

WaisayaratChoi J. Difference of Pandemic Endemic Epidemic and Outbreak?. Magazine@ Rama. 2020;38(4):26-27. (in Thai)

Yongchaiyoot P, & Oumtanee A. Nurses’ Experiences of Caring for Patients with COVID-19. Journal of The Royal Thai Army Nurses. 2023;24(2):162-70. (in Thai)

KJ, Hong HL, & Kim EJ. The association between mortality and the oxygen saturation and fraction of inhaled oxygen in patients requiring oxygen therapy due to COVID-19 associated pneumonia. Journal of Tuberculosis and Respiratory Diseases (Seoul). 2021; 84(2): 125-33; Doi: 10.4046/trd.2020.0126.

Shimizu M, & Hashimoto S. Peripheral oxygen saturation to inspiratory oxygen fraction ratio based identification of critically ill coronavirus disease patients for early therapeutic interventions. Journal of Anesthesia. 2021; 35(6): 827–36; Doi: 10.1007/s00540-021-02986-w.

Albitar O , Ballouze R, Ooi JP, Maisharah S, & Ghadzi S. Risk factors for mortality among COVID-19 patients. Journal of Diabetes Research and Clinical Practice. 2020; 166(1): 1-5; Doi: 10.1016/j.diabres.2020.108293.

Srichaiprawat T. Factor associated with deaths due to coronavirus disease 2019 in Nonthaburi province. Department of health Service Support Journal. 2023 ;19(1): 47-60. (in Thai)

Anand A, Sandefur J, & Subramanian A. Three new estimates of India’s all cause excess mortality during the COVID-19 pandemic. Center for Global Development. 2021;1(2) : 1-23.

Singh AK, Gupta R, & Misra A. Comorbidities in COVID-19: Outcomes in hypertensive cohort and controversies with renin angiotensin system blockers. Journal of Diabetes & metabolic syndrome. 2020; 14(4):283-87; Doi : 10.1016/j.dsx.2020.03.016

Banchongcharoenlert S, & Chumchuen P. Case Fetal Rate and Factors Associated with Deaths due to COVID-19 in Damnoen Saduak Hospital, Ratchaburi Province. Journal of Research for Health Improvement and Quality of Life. 2022; 2(1):25-37. (in Thai)

Department of disease control. Situation Patient’s COVID 19 in Thailand update on 16 June 2024. (Nonthaburi): Ministry of Public Health; 2024. (in Thai)

Krejcie VR, & Morgan WD. Determining sample size for research activity. Educ Psychol Meas. 1970.

Adams JY, Rogers AJ, Schuler A, Marelich GP, Fresco JM, Taylor SL, et al. Association between peripheral blood oxygen saturation (SpO2)/ Fraction of inspired oxygen (Fio2) ratio time at risk and hospital mortality in mechanically ventilated patients. The Permanente journal. 2020; 24(19): 1-7; Doi: 10.7812/TPP/19.113.

Bootthumpan O, Lavin W, & Yooyadmak P. Factors related to mortality among patients with COVID-19 in the intermediate care unit. Health Science Journal of Thailand. 2023: 6(1): 27-33 (in Thai)

Wang L, Li X, Chen H, YanS, Li D, Li Y, et al. Coronavirus disease 19 infection does not result in acute kidney injury: An analysis of 116 hospitalized patients from Wuhan, China. American journal of nephrology. 2020; 51(5):343-48; Doi : 10.1159/000507471.

Frederick KH, Petermann-Rocha F, Gray SR, Jani BD, Katikireddi SV, Niedzwiedz CL, et al. Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants. Public Library of Science. 2020;15(11):1-11; Doi: 10.1371/journal.pone.0241824.

Huang YQ, Gou R, Diao YS, Yin QH, Fan WX, et al. Charlson comorbidity index helps predict the risk of mortality for patients with type 2 diabetic nephropathy. J Zhejiang Univ Sci B. 2014;15(1):58-66. doi: 10.1631/jzus.B1300109.

Sangsa N. Factors Associated with Mortality in Patients with Coronavirus 2019 (COVID-19) Infection at Roi Et Hospital. Srinagarind Medical Journal. 2022; 37(5): 504-17. (in Thai)

Bernal JL, Andrews N, Gower C, Robertson C, Stowe J, Tessier E, et al. Effectiveness of the Pfizer-BioNTech and Oxford-Astra Zeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study. British medical journal. 2021;373:1-10; Doi: 10.1136/bmj.n1088.

Kawila R. Clinical effectiveness of remdesivir in the treatment of moderate to severe and critical COVID-19 Infections: a retrospective study. Journal of Nakornping Hospital. 2021;12(2): 1-13. (in Thai)

Paranjape N, Husain M, Priestley J, Koonjah Y, Watts C, Havlik J. Early Use of Remdesivir in Patients Hospitalized With COVID-19 Improves Clinical Outcomes: A Retrospective Observational Study. Infectious diseases in clinical practice. 2021;29(5):282-6; Doi: 10.1097/ IPC.0000000000001023.

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Published

12-04-2025

How to Cite

1.
Bootthumpan O, Klinungkab K, Panasittivana V, Donthong T, Lavin W. Factors affecting Mortality in Patients with COVID-19: After the Declaration of an Endemic Disease. J Royal Thai Army Nurses [internet]. 2025 Apr. 12 [cited 2025 Dec. 25];26(1):331-7. available from: https://he01.tci-thaijo.org/index.php/JRTAN/article/view/274982

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Research Articles