COVID-19 Vaccine and Pregnancy
Keywords:
Covid-19, Pregnant, Postpartum women, VaccineAbstract
COVID-19 epidemic severely affects the global health system and the economy. All countries have recognized the importance of campaigning for people of all ages to get vaccinated as quickly as possible. This is because the vaccine is safe and highly effective in preventing infection and reducing the severity of the disease. However, among pregnant and postpartum women, the rate of vaccination remains relatively low because they lack knowledge of the efficacy of vaccines and fear that the vaccine will harm the baby. Therefore, they decided to refuse vaccination, which increases the risk of serious complications when contracting COVID-19. However, vaccination is voluntary, pregnant women should be counseled or advised on COVID-19 vaccination to use for decision making.
Therefore, nurses are important people who should encourage pregnant women and postpartum women to get vaccinated against COVID-19 to prevent infection and reduce the severity of the disease by presenting empirical evidence on the efficacy and safety of vaccines, encourage family members to participate in supporting pregnant women, provide information about vaccination principles and establishing a system for continuous symptom monitoring, so that pregnant women can be confident and willing to receive vaccinations. This will benefit the health of pregnant women and babies in the current situation of the COVID-19 epidemic.
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References
Department of disease control. Guidelines for vaccinating against COVID-19 in an outbreak situation in 2021 of Thailand (revised 2nd edition). Thailand: TS interprint; 2021. (in Thai)
Zambrano LD, Ellington S, Strid P, Galang RR, Oduyebo T, Tong VT, et al. Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status - United States, january 22–october
, 2020. MMWR Morb Mortal Wkly Rep. 2020; 69 (44): 1641-7.
Collin J, Bystrom E, Carnahan A, Ahrne M. Public health agency of Sweden’s brief report: pregnant and postpartum women with severe acute respiratory syndrome coronavirus 2 infection in intensive care in Sweden. Acta Obstet Gynecol Scand. 2020; 9, 819–22. doi: 10.1111/aogs.13901
Wattanayingchareonchai S. The trend of COVID-19 infection among pregnant women in Thailand. Department of Health, Ministry of Public Health. 2022. (in Thai)
Ghamri RA, Othman SS, Alhiniah MH, Alelyani RH, Badawi AM, Alshahrani AA. Acceptance of COVID-19 vaccine and associated factors among pregnant women in Saudi Arabia. Patient Prefer Adherence. 2022; 16: 861–73.
Ayhan SG, Oluklu D, Atalay A, Beser DM, Tanacan A. COVID-19 vaccine acceptance in pregnant women. Int J Gynaecol Obstet. 2021; 154 (2): 291–6.
Yuki K, Fujiogi M, Koutsogiannaki S. COVID-19 pathophysiology: a review. Clin Immunol. 2020; 215: 108427. doi: 10.1016/j.clim.2020. 108427
Wastnedge EAN, Reynolds RM, van Boeckel SR, et al. Pregnancy and COVID-19. Physiol Rev. 2021; 101 (1): 303-318. doi: 10.1152/ physrev.00024.2020
Department of Medical Services. CPG COVID-19 for doctors and health workers. Department of Medical Services, Ministry of Public Health. 2021. (in Thai)
Kotlyar AM, Grechukhina O, Chen A, Popkhadze S, Grimshaw A, Tal O, et al. Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis. Am J Obstet Gynecol. 2021 Jan; 224 (1): 35-53. doi: 10.1016/j.ajog.2020.07.049
Duncombe CJ, McCulloch DJ, Shuey KD, Logue JK, Franko NM, Wolf CR, et al. Pregnancy and COVID-19. J Clin Virol. 2021 Sep; 142: 104916. doi: 10.1016/j.jcv.2021.104916
Villar J, Ariff S, Gunier RB, Thiruvengadam R, Rauch S, Kholin A, et al. Maternal and neonatal morbidity and mortality among pregnant women with and without COVID-19 infection. JAMA Pediatr. 2021; 175 (8): 817-26. doi: 10.1001/jamapediatrics.2021.1050
Shimabukuro TT, Kim SY, Myers TR, Moro PL, Oduyebo T, Panagiotakopoulos L, et al. Preliminary findings of mRNA Covid-19 vaccine safety in pregnant persons. N Engl J Med. 2021. 384 (24): 2273-2282. doi: 10.1056/ NEJMoa2104983
Gray KJ, Bordt EA, Atyeo C, Elovitz MA, Alter G, Edlow AG, et al. Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study. Am J Obstet Gynecol. 2021 Sep; 225 (3): 303. e1-303.e17. doi: 10.1016/j.ajog.2021.03.023
AstraZeneca. AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis. 2021.
Palacios R, Batista AP, Albuquerque CSN, Patiño EG, Santos JP, Conde MTRS, et al. Efficacy and safety of a COVID-19 inactivated vaccine in healthcare professionals in brazil: The PROFISCOV Study. SRRN. 2021 april.
World Health Organization. Evidence Assessment: Sinopharm/BBIBP COVID-19 vaccine. Geneva, Switzerland. 2021
Sutton D, D’Alton M, Zhang Y, Kahe K, Cepin A, Goffman D, et al. COVID-19 vaccine acceptance among pregnant, breastfeed ing and non-pregnant reproductive aged women. Am J Obstet Gynecol MFM. 2021 sep; 3 (5): 100403. doi:10.1016/j.ajogmf.2021.100403
Pairat K, Phaloprakarn C. Acceptance of COVID-19 vaccination during pregnancy among Thai pregnant women and their spouses: a prospective survey. Reproductive Health. 2022; 19: 74. doi: doi:10.1186/s12978-022-01383-0
Citu IM, Citu C, Gorun F, et al. The risk of spontaneous abortion does not increase following first trimester mRNA COVID-19 vaccination. J Clin Med. 2022; 11 (6): 1698. doi: 10.3390/jcm11061698
Peretz-Machluf R, Hirsh-Yechezkel G, ZaslavskyPaltiel I, et al. Obstetric and neonatal outcomes following COVID-19 vaccination in pregnancy. J Clin Med. 2022; 11(9): 2540. doi: 10.3390/jcm11092540
The royal Thai college of obstetricians and gynaecologists. RTCOG Clinical practice guideline management of COVID-19 infection in pregnancy (version 6). The royal Thai college of obstetricians and gynaecologists. 2022. (in Thai)
Blakeway H, Prasad S, Kalafat E, et al. COVID-19 vaccination during pregnancy: coverage and safety. Am J Obstet Gynecol. 2022; 226 (2): 236. e1-236.e14.
Morgan JA, Jr JRB, Martin JK, Mussarat N, Chawla HK, Puri P, et al. Maternal outcomes after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated compared with unvaccinated pregnant patients. Obstet Gynecol. 2022; 139 (1): 107-9.
Schwartz DA. Stillbirth after COVID-19 in unvaccinated mothers can result from SARS-CoV-2 placentitis, placental insufficiency, and hypoxic ischemic fetal demise, not direct fetal infection: potential role of maternal vaccination in pregnancy. Viruses. 2022; 23; 14 (3): 458.
Fenizia C, Biasin M, Cetin I, et al. Analysis of SARS-CoV-2 vertical transmission during pregnancy. Nat Commun. 2020; 11 (1): 5128. doi:10.1038/s41467-020-18933-4
Yang YJ, Murphy EA, Singh S, Sukhu AC, Wolfe I, Adurty S, et al. Association of gestational age at Coronavirus disease 2019 (COVID-19) vaccination, history of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, and a vaccine booster dose with maternal and umbilical cord antibody levels at delivery.Obstet Gynecol. 2022; 139 (3): 373-380.
American College of Obstetricians and Gynecologists. COVID-19 vaccination considerations for obstetric–gynecologic care. Practice Advisory, ACOG. 2022.
Utthiya P, Sereewichayasawad N. Roles of Nurses in home health care unit in the COVID 2019 pandemic situation. Journal Royal Thai Army Nurses, 2022;23(2):25-32. (in Thai)
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