Relationships between Selected Factors and Adherence to Antiretroviral Therapy among People Living with HIV

Authors

  • Aomtip Ponboobpha Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University https://orcid.org/0000-0001-8622-167X
  • Wantana Maneesriwongul Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Wanna Sa-nongdej Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University

Keywords:

People living with HIV, Antiretroviral therapy adherence, Knowledge about ART, Perceived needs for ART, Perceived barriers to ART

Abstract

A descriptive correlation study was conducted to explore relationships between selected factors and antiretroviral therapy adherence among people living with HIV. Selecting a specific sample group according to the inclusion criteria. A sample comprised of 220 people living with HIV who started antiretroviral therapy (ART). Data were collected by using a set of self-administered questionnaires. The content validity of interviewing forms were .96, .94 and .95 respectively and reliabilities were .94, .86 และ .84 respectively Pearson’s product- moment correlation and Spearman’s correlation were used to analyzing data.

This study revealed that age, education, and perceived needs for treatment were positively related to antiretroviral therapy adherence among people living with HIV (r = .223, p< .01; r = .164, p< .05; rs = .192, p< .05 respectively). While, the perceived barrier was negatively related to antiretroviral therapy adherence (r = -. 264, p< .05). Other factors were not significantly related to antiretroviral therapy adherence.
The findings from this study suggested that nursing interventions enhancing antiretroviral therapy adherence should be provided early to prepare people living with HIV, especially those who are younger age, reported to have low perceived ART needs, and have high perceived barriers to ART.

Author Biographies

Aomtip Ponboobpha, Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University

 

 

Wantana Maneesriwongul, Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University

 

 

Wanna Sa-nongdej, Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University

 

 

References

Bureau of AIDS Tuberculosis and STDs Department of disease control. Guidelines for the treatment and prevention of HIV infection in Thailand 2017. Nonthaburi: Agricultural Cooperative Society of Thailand. printing house 2017; 33-137. (in Thai)

The Joint United Nations Program on HIV and AIDS (UNAIDS). UNAIDS: Fast-Track cities reaching the 90–90–90 targets. UNAIDS. 2016.

Department of disease control, Ministry of public. Thailand National Guidelines on HIV/AIDS Treatment and Prevention. Nonthaburi. 2017: Agricultural Cooperative Society of Thailand. printing house 2017. (in Thai)

ASEAN Institute of Health Development Mahidol University. Assessment results. in the evaluation report The project “Evaluation of the treatment Caring, helping and supporting people living with HIV, AIDS patients in Thailand”. Nakhon Pathom: Patcharaphon Shop 2014; p. 36,101. (in Thai).

Arnedo-Valero M., Garcia F., Gil C., Guila T., Fumero E., Castro P., Blanco JL., Miró JM., Pumarola T. and Gatell JM. Risk of selecting de novo drug-resistance mutations during structured treatment interruptions in patients with chronic HIV infection. Clinical infectious diseases. 2005; 41(6): 883-90.

Sprangers MA., van der Ende M., Schreij G., de Wolf F. and Nieuwkerk PT. Lower perceived necessity of HAART predicts lower treatment adherence and worse virological response in the ATHENA cohort. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2008; 49(4): 460-2.

Limtoprasert S. Developing the participatory working program for people living with HIV and AIDS network in the holistic centres of hospitals in Ubon Ratchathani. ACADEMIC JOURNAL BANGKOKTHONBURI UNIVERSITY 2013; 2(2): 176-191. (in Thai)

Protopopescu C., Carrieri M.P., Raffi F., Picard O., Hardel L., Piroth L., Jadand C., Pierret J., Spire B. and Leport C. Brief report: prolonged viral suppression over a 12-year follow-up of HIV-infected patients: the persistent impact of adherence at 4 months after initiation of combined antiretroviral therapy in the ANRS CO8 APROCO-COPILOTE cohort. JAIDS Journal of Acquired Immune Deficiency Syndromes 2017; 74(3): 293-297.

Ickovics JR. and Meade CS. Adherence to antiretroviral therapy among patients with HIV: a critical link between behavioral and biomedical sciences. Journal of acquired immune deficiency syndromes. (1999). 2002; 31: S98-102.

Orathai P. and Phumonsakun S. Power analysis and sample size estimation using G*power program. [thesis]. Bangkok: Thammasat University; 2013. (in Thai)

Maneesriwongul W. Adherence.In Ningsanond P., Chasombat S., Jirawattanapisal T. and Maisuwan S. (Eds.), Summary of lessons on promoting the continued use of antiretroviral drugs for HIV-infected and HIV-infected patients. p.9. Bangkok. The Agricultural Cooperative Society of Thailand Printing House. 2004. (in Thai)

Kumkrong Ch., Maneesriwongul W. and Janpanish P. Relationships of Health Literacy and Knowledge about Antiretroviral Therapy to Medication Adherence among People Living with HIV. Kuakarun Journal of Nursing. 2014; 21(2): 221-228. (in Thai)

Maneesriwongul W., Sa-nongdej W., Ponboobpha A. and Pakdee J. A study of access to HIV-testing and access to antiretroviral therapy (under new policy providing treatment regardless of CD4 count) [Unpublished manuscript]. N.p.; 2020. (in Thai)

Srirach C., Boonshuyar C. and Pacheun O. Health Behaviors and Adherence to Antiretroviral Drug among People Living with Human Immunodeficiency Virus. Journal of Nursing, Siam University 2018; 19 (37): 39-55. (in Thai)

Ruansawang P., Chongthawonsatid S., Prasithsirikul W., Limjaroen K., Muangpaisan K. and Siriwarothai Y. Demographic Factors, Stage of Disease and Adherence of Antiretroviral Drug Therapy in HIV/AIDS. Disease Control Journal 2011; 37(1): 18-26. (in Thai)

Teerawatanasuk N., Chaikoolvatana A. and Pealkum S. The relationship between demographic and health factors, social support factors and antiretroviral adherence in HIV/ AIDS patients, Um-Najaroen Province, Thailand. IJPS 2012; 8(3): 1-3. (in Thai)

Chotisen O., Praditbatuka S. and Cheevakasamsook A. Factors Related to People living with HIV/ AIDS Behaviors at Sirindhorn Hospital, Medical Service Department, Bangkok Metropolitan Administration. Journal of The Royal Thai Army Nurses 2015; 16(1), 41–50. (in Thai)

Horne R., Chapman SC., Parham R., Freemantle N., Forbes A. and Cooper V. Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the NecessityConcerns Framework. PloS one. 2013; 8(12):1-24.

Chaichan M., Maneesriwongul W. and Jannepanish Visudtibhan P. Relationships between Personal Characteristics, Barriers to Access to Care, and Perceived Stigma and Medication Adherence among People Living with HIV. Journal of Phrapokklao Nursing College 2015; 26(2): 78-92. (in Thai)

Prajankett O. The Related Factors with Adherence to Antiretroviral Therapy in People Living with HIV/AIDS Attending Infectious Division, Department of Medicine, Phramongkutklao Hospital. Royal Thai Army Medical Journal. 2012; 65(2): 95-102. (in Thai)

Downloads

Published

02-01-2023

How to Cite

1.
Ponboobpha A, Maneesriwongul W, Sa-nongdej W. Relationships between Selected Factors and Adherence to Antiretroviral Therapy among People Living with HIV. J Royal Thai Army Nurses [Internet]. 2023 Jan. 2 [cited 2024 Nov. 19];23(3):314-22. Available from: https://he01.tci-thaijo.org/index.php/JRTAN/article/view/256344

Issue

Section

Research Articles