Albumin and Normalized Protein Catabolic Rate (nPCR) in Patients with End Stage Renal Disease Receiving Hemodialysis: 24 Months Retrospective Study

Authors

  • Chanita Buathong Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Wasan Trakulsuntornchai Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Teepatad Chintapanyakun Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Chitimaporn Janphram Faculty of Medicine Ramathibodi Hospital, Mahidol University

Keywords:

Albumin level, Normalized protein catabolic rate, Patients with end stage renal disease received hemodialysis

Abstract

The purposes of this retrospective study were to study albumin and normalized protein catabolic rate (nPCR) in patients with end stage renal disease received hemodialysis and to compare theirs classified by gender, age, comorbidity, frequency of hemodialysis, and hemodialysis adequacy. Data were collected from 105 patients with end stage renal disease received hemodialysis at the hemodialysis units in Somdech Phra Debaratana Medical Center and Queen Sirikit Medical Center, Faculty of Medicine, Ramathibodi Hospital. The data were purposive selection from January 1, 2017 to December 31, 2018. The research instruments were composed of demographic information, albumin level, and normalized protein catabolic rate. Data were analyzed using descriptive and Mann-Whitney U test statistics.

Findings indicated that 1) the mean score of albumin level was 40.00 mg/dL and normalized protein catabolic rate was 1.00 g/kg/day 2) the mean score of albumin level and normalized protein catabolic rate were statistically significant at the .05 level classified by comorbidity, frequency of hemodialysis, and hemodialysis adequacy.

References

Thurlow JS, Joshi M, Yan G, et al. Global epidemiology of end-stage kidney disease and disparities in kidney replacement therapy. Am J Nephrol 2021;52(2):98-107.

Luyckx VA, Tonelli M, Stanifer JW. The global burden of kidney disease and the sustainable developmentgoals.WorldHealthOrganization 2018; 96.

Nephrology Society of Thailand. Clinical practice recommendation for comprehensive conservative care in chronic kidney disease. Bangkok: Nephrology Society of Thailand; 2017. (in Thai).

Chuasuwan A., Lumpaopong A. Thailand renal replacementtherapyyear2016-2019.Bangkok: NephrologySocietyofThailand;2019.(inThai).

Thanakitcharu P. Current situation of chronic kidney disease in Thailand. Journal of the Department of Medical Services 2015; 5: 5-17. (in Thai).

Wungrath J, Rerkkasem K, Saengyo S, Pongtam S, PinmarsN.Factorspredictingfoodconsumption behavior of hemodialysis patients with end stage renal disease at Maharaj Nakorn Chiang Mai Hospital. Journal of Health Systems Research 2018; 12(4): 625-35. (in Thai).

Lodebo BT, Shah A, Kopple JD. Is it important to prevent and treat protein-energy wasting in chronic kidney disease and chronic dialysis patients?. J Ren Nutr 2018; 28(6): 369-79.

Rattanaruang R, Prapaipanich W, Visudtibhan PJ., Lekhyananda S. Effects of a food intake focused on protein promoting program in end-stage renal disease patients undergoing hemodialysis. Rama Nurs J 2014; 20(3): 341-55. (in Thai).

Oliveira TS, Valente AT, Caetano CG, Garagarza CA. Nutritional parameters as mortality predictors in haemodialysis: Differences between genders. Journal of Renal Care 2018; 43(2): 83-91.

Yajima T, Arao M, Yajima K, Takahashi H, Yasuda K. The associations of fat tissue and muscle mass indices with all-cause mortality in patients undergoing hemodialysis. PLoS One 2019 13; 14(2): e0211988.

Windahl K, Faxén Irving G, Almquist T, Lidén MK, van de Luijtgaarden M, Chesnaye NC, Voskamp P, Prevalence and risk of protein-energy wasting assessed by subjective global assessment in older adults with advanced chronic kidney disease: results from the EQUAL Study. J Ren Nutr 2018; 28(3): 165-74.

National Kidney Foundation. KDIGO 2012 Clinical practice guideline for the evaluation and management of chronic kidney disease. Journal of The International Society of Nephrology 2013; 3(1): 1-150.

Nephrology Society of Thailand. Guideline of hemodialysis and plasma filtration for kidney disease patients. Bangkok: Nephrology Society of Thailand; 2018. (in Thai).

Howell DC. Statistical methods for psychology. 8th ed. Belmont, California: Wadsworth Cengage Learning; 2013.

Wongsaree C, Praneetham W. The study of relationship and factors influencing of dietary and fluid consumption among end stage renal disease patient receiving hemodialysis. Journal of The Royal Thai Army Nurses 2018; 19(3): 117-25. (in Thai).

Nephrology Society of Thailand. Clinical practice recommendation for nutritional management in adult kidney patients 2018. Bangkok: Nephrology Society of Thailand; 2018. (in Thai).

Chinnoros, S. Malnutrition status of hemodialysis patients. Journal of Health and Health Management 2019; 5(1): 1-8. (in Thai).

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Published

30-12-2021

How to Cite

1.
Buathong C, Trakulsuntornchai W, Chintapanyakun T, Janphram C. Albumin and Normalized Protein Catabolic Rate (nPCR) in Patients with End Stage Renal Disease Receiving Hemodialysis: 24 Months Retrospective Study. J Royal Thai Army Nurses [Internet]. 2021 Dec. 30 [cited 2024 Apr. 20];22(3):433-42. Available from: https://he01.tci-thaijo.org/index.php/JRTAN/article/view/249971

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Section

Research Articles