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Approximately 50 percent of infants were diagnosed neonatal jaundice after birth, which phototherapy is an important method to reduce the bilirubin level. However, side effects of phototherapy, for example, baby bronze syndrome and childhood asthma could endanger those infants. Therefore, reducing the duration of phototherapy could be advantageous for them. Also, some researchers found applying Kangaroo Mother Care (KMC) in newborns receiving phototherapy could shorten the phototherapy period. The purpose of this study is to assess the available evidence comparing the duration of phototherapy when applying KMC in infants during receiving phototherapy. For this review, the Cochrane approach was used to report. The studies were retrieved from four databases: MEDLINE, EMBASE, CINAHL, and CENTRAL between 10 and 18 March 2018. The Cochrane Collaboration’s tool were applied to assess the risk of bias through all studies. Moreover, the meta-analysis was used for synthesizing the data. The results were two RCTs studies which a total of 322 infants were included in the analysis part. The finding found that applying KMC could reduce the duration pf phototherapy in infants with jaundice. n conclusion, even the finding shows the application of KMC can reduce the duration of phototherapy in infants with jaundice, the level of the evidence is very low because the high risk of bias of both papers. However, there is no disadvantages from applying KMC. Therefore, using KMC during receiving phototherapy is strongly recommended with the low quality of the evidence. Furthermore, rigorous RCTs studies with generate the high quality evidence for this article are required.
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บทความหรือข้อคิดเห็นใดใดที่ปรากฏในวารสารพยาบาลทหารบกเป็นวรรณกรรมของผู้เขียน ซึ่งบรรณาธิการหรือสมาคมพยาบาลทหารบก ไม่จำเป็นต้องเห็นด้วย
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of the editor or Royal Thai Army Nurses Association.
2. Levene MI, Tudehope DI, Sinha SK. 4th ed. Essential neonatal medicine. Oxford: Blackwell Publishing; 2008.
3. Aspberg S, Dahlquist G, Kahan T, Källén B. Confirmed association between neonatal phototherapy or neonatal icterus and risk of childhood asthma. Pediatric Allergy And Immunology. 2010; 21(4): 733-739.
4. Heidarzadeh AM, Mosaiebi Z, Movahedian A, Aabedi A. The relation between neonatal phototherapy and childhood asthma. Indian Journal Allergy Asthma Immunology. 2011; 25(2): 97-101.
5. Itoh S, Okada H, Kuboi T, Kusaka t. Phototherapy for neonatal hyperbilirubinemia. Pediatrics International. 2017;59, 959-966.
6. Khan M, Malik KA, Bai R. Hypocalcemia in jaundiced neonates receiving phototherapy. Pakistan Journal of Medical Scinces. 2016; 32(6):1449-1452.
7. Goudarzvand L, Dabirian A, Nourian M, Jafarimanesh H, Ranjbaran M. Comparison of the conventional phototherapy and phototherapy along with Kangaroo mother care on cutaneous bilirubin of neonates with physiological jaundice. J Matern Fetal Neonatal Med. 2019; 32(8): 1280-1284.
8. Larma’i NR, Ahmadpour-kacho M, Pasha YZ, Hajiahmadi M. The effect of Kangaroo Mother Care on the duration of phototherapy in term infants with Hyperbilirubinemia. Journal of Babol University of Medical Sciences. 2016;18(6): 15-20.
9. Li X, Zhang Y, Li W. Kangaroo Mother Care could significantly reduce the duration of phototherapy for babies with jaundice. International Journal of Clinical and Experimental Medicine. 2017; 10(1): 1690-1695.
10. Nirmala P, Rekha S, Washington M. Kangaroo Mother Care: Effect and perception of mothers and health personnel. Journal of Neonatal Nursing. 2006; 12(5): 177-184.
11. Kelly DA, Stanton A. Jaundice in babies: implications for community screening for biliary atresia. British Medical Journal. 1995;310, 1772-1773.
12. Higgins & Green S. Cochrane handbook for systematic reviews of intervention. West Sussex: John Wiley & Sons Ltd. 2008.
13. Ludington-Hoe S, Swinth J. Kangaroo Mother Care During Phototherapy: Effect on Bilirubin Profile. Neonatal Network. 2001; 20(5). Available from:
14. Samra NM, Taweel AE, Cadwell K. The effect of kangaroo mother care on the duration of phototherapy of infants re-admitted for neonatal jaundice. The Journal of Maternal-Fetal and Neonatal Medicine.2012; 25(8): 1354-1357.
15. Higgins JP, Altman DG. Assessing risk of bias in included studies. In J. P. Higgins, & S. Green, Cochrane handbook for systematic reviews of interventions. West Sussex: John Wiley & Sons Ltd; 2008.
16. Bowling A. The philosophical framework of measurement. London: Mc Graw-Hill Education; 2014.
17. Gluud LL. Bias in Clinical Intervention Research. American Journal of Epidemiology. 2006; 163(6): 493-501.
18. Deeks JJ, Higgins JP, Altman DG. Analysing data and undertaking meta-analysis. In J. P. Hggins, & S. Green, Cochrane Handbook for Systematic
Reviews of Interventions. West Sussex: John Wiley & Sons Ltd; (2008).
19. Choi SW, Lam DM. Funnels for publication bias – have we lost the plot? Anesthesia. 2015; 71(3): 338-341.
20. Sterne JA, Egger M, Moher D. Addressing reporting. In J. P. Higgins, & S. Green, Cochrane Handbook for Systematic Reviews of Interventions
(pp. 297-334). West Sussex: John Wiley & Sons, Ltd; 2008.
21. Thaler K, Kien C, Nussbaumer B, Noord MG, Griebler U, Klerings I, Gartlehner G. Inadequate use and regulation of interventions against publication bias decreases their effectiveness: a systematic review. Journal of Clinical Epidemiology; 2017: 68(7), 792-802.
22. Schünemann HJ, Oxman A D, Vist GE, Higgins JP, Deeks JJ, Glasziou P, Guyatt GH. Interpreting results and drawing conclusions. In J. P. Higgins, & S. Green, Cochrane Handbook for Systematic Reviews of Interventions. West Sussex: John Wiley & Sons, Ltd; 2008.
23. Lertsakornsiri M., Saibae S., Charoenwoodhiphong S. The effect of nursing model integrated with family support and empowerment on breastfeeding in the first-time teenage postpartum mothers. Journal of The Royal Thai Army Nurses. 2018;19 (Supplement): 129-138. (in Thai)
24. Apartsakun P., Wongphinit U. Effectiveness of “Breastfeeding Support Package” to the Ability to breastfeed among postpartum women. Journal of The Royal Thai Army Nurses. 2019;20(2): 102-111. (in Thai)
25. Apartsakun P. Value of Breastfeeding in Thai mothers: Nursing roles. Journal of The Royal Thai Army Nurses. 2018;19 (Supplement): 53-60. (in Thai)