Development and Validation of Mild Behavioral Impairment Checklist-Thai Version in The Psychiatric Clinic and The Memory Clinic
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Abstract
Objective: To develop and examine the psychometric properties of Thai versioned Mild Behavioral Impairment Checklist (MBI-C).
Methods: The process of translating the MBI-C into Thai involved back-translation, cross-cultural adaptation, field testing of the pre-final version, and final adjustments. A total of 92 participants were recruited from patients attending the psychiatric and memory clinics at Ramathibodi Hospital. A research assistant collected demographic and MBI-C data, while attending physicians independently diagnosed MBI according to the ISTAART criteria. The comparison of MBI-C scores was performed using the Kruskal-Wallis test. Internal consistency of the MBI-C total and subdomain scores was assessed using Cronbach’s alpha coefficient. The optimal cut-off point, sensitivity, and specificity were identified using the Youden index (J). The main analyses were conducted on the total sample. Exploratory analyses were restricted to subsamples with characteristics that might influence MBI-C performance: those with mild cognitive impairment (MCI) and with caregivers as informants.
Results: The mean age of the MBI group (mean = 69.9, SD = 9) was significantly higher than that of the non-MBI group (mean = 64.2, SD = 8.5, p = 0.035). There was no statistically significant difference in MBI-C total scores between the MBI and non-MBI groups (AUC = 0.61, 95% CI = 0.49 - 0.73). However, the social appropriateness subscale exhibited a significant AUC (0.59, 95% CI = 0.53 - 0.66). Exploratory analysis in the MCI subgroup revealed a significant AUC of the MBI-C total score (0.68, 95% CI = 0.51 - 0.86). The optimal cut-off point was 4, with a sensitivity of 61% and a specificity of 67%. Furthermore, the analyses restricted to the caregiver-derived data of the MCI subsample showed improved performance of MBI-C subdomains of emotional regulation, impulse control, social appropriateness, and perception/thought content.
Conclusion: The Thai-version MBI-C has good internal consistency except for the perception/thought content subdomain. The social appropriateness and the perception/thought content subdomains could differentiate MBI in the total sample, although below the level of clinical usefulness. Its performance might be improved in people with MCI, particularly when the data were collected from caregivers, warranting further investigation.
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