Risk Factors for Delirium Tremens in Patients with Alcohol Withdrawal Syndrome in Psychiatric Ward
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Abstract
Objective: To study the risks factors related to delirium tremens in patients with alcohol withdrawal syndrome in Psychiatric ward.
Methodology: The Retrospective cohort study was done for 209 patients who were diagnosed with alcohol dependence and admitted in Psychiatry department of Phramongkutklao Hospital between December of 2005 to April 2019. The questionnaire was applied including general information, medical information record, alcohol consumed record, information about rating scale of symptom from MINDs Score and laboratory examinations.
Result: The risk factors among Alcohol withdrawal syndrome’s patient statistically significant consisted 14 items which are, reason for stopping consumption unintentional and unforced (P < 0.001), past history of severe alcohol withdrawal (P<0.001), past history of Delirium tremens (P=0.016), past history of alcohol withdrawal seizure (P=0.001), had treated by fixed-dose regimen (P< 0.001), medicine of detoxification (benzodiazepine / diazepam IV) (P< 0.001), the highest average temperature in the first 24 hours (P=0.002), agitation (P=0.047), alcohol withdrawal seizure (P<0.001), disoriented (P= 0.035), blood level of platelets (P<0.001), blood level of Potassium (P<0.001), blood level of Creatinine (P=0.031) , and blood level of AST (P<0.001). Multiple logistic regression was done factors that increasing severe alcohol withdrawal are reason for stopping consumption unintentional and unforced, alcohol withdrawal seizure, past history of Delirium tremens, and temperature and the factors that preventing severe alcohol withdrawal among Alcohol withdrawal syndrome’s patient are average of platelets and blood Potassium level.
Conclusion:The study found that the risk factors related to severe alcohol withdrawal is more increasing than researches in the formal time of Thailand included factors of reason for stopping consumption, past history of Delirium tremens, the highest average temperature in the first 24 hours, alcohol withdrawal seizure, blood platelets level and blood Potassium level. From all of the factors, we could be prognosticated severe alcohol withdrawal among Alcohol withdrawal syndrome’s patient.
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References
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