Efficacy of Psychosocial Intervention for Preventing Depression In Older Adult Patients with Cancers Undergoing Chemotherapy Treatment

Main Article Content

จามรี ณ บางช้าง
วริญญา อรรถยุกติ


Background : Older adults diagnosed with cancer has grown in prevalence with serious and chronic disease a common factor of mental health problems. Depression among older patients with cancers affects the prognosis and compliance of cancer treatments. Psychosocial intervention is the option for supporting and encouraging patients to have healthy coping skills and good quality of life.

Methods : A quasi-experimental study was conducted on two groups. Subjects were over 60 years old with diagnosed breast, lung and colorectal cancer and each group was consisting of 90 patients for the control group and 90 patients for the experimental group. During a six-week period, the control group received normal care while the trial group received the multidisciplinary care, including psychosocial intervention. The primary mental health issue measured was depression (Thai Geriatric Depression Scale: TGDS-15). Data analysis used independent t-test, fisher’s exact test, and chi-square at 0 3 and 6 weeks to compare difference in both groups.

Results : 180 patients total were enrolled into the study with mean aged of 67.07 years old (60-81), female (56.7%) which basic characteristics not found to be significantly different between the control and experimental groups. Depression was also not found be significantly different in both groups.

Conclusion : Psychosocial intervention not shown to be significantly effective for preventing depression in older patients with cancers undergoing chemotherapy treatment over the course of six weeks, but further study should screen for depression and enroll patients in treatment for a length longer than the 6 weeks of this study.


Download data is not yet available.

Article Details

How to Cite
ณ บางช้าง จ., & อรรถยุกติ ว. (2019). Efficacy of Psychosocial Intervention for Preventing Depression In Older Adult Patients with Cancers Undergoing Chemotherapy Treatment. Journal of the Psychiatric Association of Thailand, 64(4), 299–308. Retrieved from https://he01.tci-thaijo.org/index.php/JPAT/article/view/231872
Original Articles


World Federation for Mental Health. Depression a global crisis World Mental Health day October 10 2012. [Accessed 2012 September 10]. Available from: http:// www. wfmh.com/2012DOCS/WMHDay%202012%20 SMALL%20FILE%20FINAL.pdf

Judd LL, Schettler PJ, Akiskal HS. The prevalence, clinical relevance, and public health significance of sub threshold depressions. Psychiatric Clinics of North America 2002; 25: 685-98.

Blazer D, Williams CD. Epidemiology of dysphoria and depression in an elderly population. Am J Psychiatry 1980; 137: 439-44.

Beekman AT, Copeland JR, Prince MJ. Review of community prevalence of depression in later life. Br J Psychiatry 1999; 174: 307-11.

Lyness JM. Treatment of depressive conditions in later life: Real-world light for dark (or dim) tunnels. JAMA 2004; 291: 1626-8.

Langa KM, Valenstein MA, Fendrick AM, Kabeto MU, Vijan S. Extent and cost of informal caregiving for older Americans with symptoms of depression. Am J Psychiatry 2004; 161: 857-63.

Pirl WF. Evidence report on the occurrence, assessment, and treatment of depression in cancer patients. J Natl Cancer Inst Monogr 2004; 32: 32-39.

Hopko DR, Bell JL, Armento ME, Robertson SM, Hunt MK, Wolf NJ, Mullane C. The phenomenology and screening of clinical depression in cancer patients. J Psychosoc Oncol 2008; 26: 31-51.

Nelson CJ, Cho C, Berk AR, Holland J, Roth AJ. Are gold standard depression measures appropriate for use in geriatric cancer patients? A systematic evaluation of self-report depression instruments used with geriatric, cancer, and geriatric cancer samples. J Clin Oncol 2010; 28: 348-56.

Lloyd-Williams M, Shiels C, Taylor F, Dennis M. Depression--an independent predictor of early death in patients with advanced cancer. J Affect Disord 2009; 113: 127-32.

Institute of Medicine. Washington, DC: National Academies Press; 2007. From Cancer Patient to Cancer Survivor: Lost in Transition. Weinberger MI, Roth AJ, Nelson CJ. Untangling the complexities of depression diagnosis in older cancer patients. Oncologist 2009; 14: 60-6.

Scogin F, McElreath L. Efficacy of psychosocial treatments for geriatric depression: a quantitative review. J Consult Clin Psychol 1994; 62: 69-74.

Frederick JT, Steinman LE, Prohaska T, Satariano WA, Bruce M, Bryant L, et al. Late Life Depression Special Interest Project Panelists. Am J Prev Med. 2007; 33: 222-49.

Walker J, Hansen CH, Martin P, Symeonides S, Gourley C, WallL, Weller D, Murray G, Sharpe M, SMaRT (Symptom Management Research Trials) Oncology-3 Team: Integrated collaborative care for major depression comorbid with a poor prognosis cancer (SMaRT Oncology-3): a multicentre randomised controlled trial in patients with lung cancer. Lancet Oncol 2014; 15: 1168-76.

Sharpe M, Walker J, Holm Hansen C, Martin P, Symeonides S, Gourley C, Wall L, Weller D, Murray G, SMaRT (Symptom Management Research Trials) Oncology-2 Team: Integrated collaborative care for comorbid major depression in patients with cancer (SMaRT Oncology-2): a multicentre randomised controlled effectiveness trial. Lancet 2014; 384: 1099-108.

Li M, Kennedy EB, Byrne N et al. Systematic review and meta-analysis of collaborative care interventions for depression in patients with cancer. Psychooncology. 2017 May; 26(5): 573-587.

Chong Guan N, Mohamed S, Kian Tiah L et al. Psychotherapy for cancer patients. Int J Psychiatry Med 2016; 51: 414-30.

Piet J, Würtzen H, Zachariae R: The effect of mindfulness-based therapy on symptoms of anxiety and depression in adult cancer patients and survivors: a systematic review and meta-analysis. J Consult Clin Psychol 2012; 80: 1007-20.

Kroenke K, Theobald D, Wu J, Norton K, Morrison G, Carpenter J, Tu W: Effect of telecare management on pain and depression in patients with cancer: a randomized trial. JAMA 2010; 304: 163-71.

Park CL, Pustejovsky JE, Trevino K et al. Effects of psychosocial interventions on meaning and purpose in adults with cancer: A systematic review and meta-analysis. Cancer 2019; 125: 2383-93.

Jarurin Pitanupong. Narrative therapy, brief individual meaning-centered psychotherapy and solution-focus brief therapy in palliative care. Songkla Med J 2015; 33: 305-13.