Comparison of Efficacy and Safety of the Ma-beedee and Standard Complete Medical-tube Feeding Formula on Nutritional Status of Patients Required Enteral Feeding
Keywords:Malnutrition, Enteral nutrition, Medical food
Malnutrition contributes to increased morbidity and mortality. Appropriate nutritional therapy can prevent malnutrition. Enteral feeding is a standard nutritional intervention given to patients who cannot get adequate nutritional requirements by volitional intake. This study aims to compare the efficacy and safety of a new standard formula, Ma-beedee, to the standard polymeric formula on the nutritional status of patients receiving enteral feeding. The study was a blind-randomized controlled trial in adult patients treated with enteral feeding. Thirty-eight patients were fed with the standard polymeric formula, while thirty-nine were fed with Ma-beedee for 14 days. The outcomes are to compare changes of body weight, pre-albumin, and other laboratory results and determine the side effects of enteral feeding. There were no significant differences in baseline characteristics of both study and control groups. Also, there were no significant differences in nutritional parameter and number of side effect from enteral feeding between 2 groups after 14 days of enteral nutrition. However, after 14 days of enteral feeding, in the Ma-beedee group, there was a statistically significant increase in pre-albumin and albumin from 17.93±6.88 to 22.50±7.26 mg/dL (p<0.0001), and 2.96±0.50 to 3.18±0.53 g/dL(p=0.0012), respectively. In the standard formula, there was a statistically significant increase in body weight from 45.46±9 to 46.30±9.34 kg (P=0.025). However, there was no statistically significant increase in prealbumin. Ma-beedee has an efficacy and safety outcomes to use as enteral feeding as the standard polymeric formula.
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