Postpartum Splenic Artery Thrombosis Followed by Splenic Rupture in Patient with Hemoglobin H Disease: A Case Report and Review Literatures
คำสำคัญ:
Artery thrombosis, Hemoglobin H Disease, Splenic ruptureบทคัดย่อ
บทคัดย่อ : ผู้ป่วยหญิงไทยอายุ 26 ปี เป็นโรค thalassemia ชนิด Hemogiobin H disease หลังคลอดบุตร 15 ชั่วโมงมีอาการปวดท้องใต้ชายโครงด้านช้ายอย่างเฉียบพลัน โดยที่ไม่มีประวัติได้รับอุบัติเหตุมาก่อน ตรวจร่างกายพบภาวะโลหิตจาง ร่วมกับกดเจ็บใต้ชายโครงด้านซ้ายและพบม้ามโตเล็กน้อย ตรวจเอกเรซ์คอมผิวเตอร์ช่องท้อง พบมี splenic artery thrombosis การตรวจหาระดับของ antithrombin I, Protein C, Protein S, Factor V leiden mutation Homocysteine และ Lupus anticoagulant พบว่าอยู่ในกณฑ์ปกติ ผู้ป่วยได้รับการรักษาด้วย low molecular weight heparin (LMWH) ในช่วงแรกและให้ Warfarin รับประทานในเวลาต่อมา
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