Syphilis in transfusion medicine: clinical staging, transfusion-transmitted risk, and blood safety in Thailand

Authors

  • Aphisit Thongthaisin National Blood Centre, Thai Red Cross Society

DOI:

https://doi.org/10.69898/jhtm.37.2027.292606

Keywords:

Syphilis, TTIs

Abstract

-

Downloads

Download data is not yet available.

References

1. Tudor ME, Al Aboud AM, Leslie SW, Gossman W. Syphilis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2026 Sep 1]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK534780/

2. Centers for Disease Control and Prevention. Syphilis. In: Sexually transmitted infections treatment guidelines [Internet]. Atlanta (GA): CDC; 2021 [cited 2026 Sep 1]. Available from: https://www.cdc.gov/std/treatment-guidelines/syphilis.htm.

3. World Health Organization. WHO guidelines for the treatment of treponema pallidum (syphilis) [Internet]. Geneva: WHO; 2016 [cited 2026 Sep 1]. Available from: https://www.who.int/publications/i/item/9789241549806.

4. Adegoke AO, Akanni O. Risk of transfusion-transmitted syphilis in a tertiary hospital in Nigeria. Niger J Basic Clin Sci. 2011;3:78-81.

5. Bloch EM. Transfusion-transmitted infections. Ann Blood. 2022;7:20.

6. Owusu-Ofori AK, Parry CM, Bates I. Transfusion-transmitted syphilis in teaching hospital, Ghana. Emerg Infect Dis. 2011;17:2080-2.

7. Zheng Y, Ye K, Ying M, He Y, Yu Q, Lan L, Xu W. Syphilis epidemic among men who have sex with men: a global systematic review and meta-analysis of prevalence, incidence, and associated factors. J Glob Health. 2024;14:04004.

8. Sharma M, Rewari BB, Aditama TY, Turlapati P, Dallabetta G, Steen R. Control of sexually transmitted infections and global elimination targets, South-East Asia Region. Bull World Health Organ. 2021;99:304-11.

9. Rattanatham R, Mala W, Kotepui KU, Masangkay FR, Rattanawan C, Lasom S, et al. A systematic review and meta-analysis of the prevalence and risk of syphilis among blood donors in Thailand. Sci Rep. 2025;15:9316. doi: 10.1038/s41598-025-94332-3.

10. World Health Organization. Global guidance on criteria and processes for validation: elimination of mother-to-child transmission of HIV, syphilis and hepatitis B virus [Internet]. 3rd ed. Geneva: WHO; 2021 [cited 2026 Sep 1]. Available from: https://www.who.int/publications/i/item/9789240039360.

11. Poobua K, Yingyong T, Jantaramanee S. Situation of syphilis in Thailand, 2025-data as of September 4, 2025. Wkly Epidemiol Surveill Rep. 2025;56:e6649.

12. Division of AIDS and STIs, Department of Disease Control, Ministry of Public Health (TH). Congenital syphilis [Internet]. Nonthaburi: Department of Disease Control; 2024 Oct 28 [cited 2026 Oct 19]. Available from: https://www.ddc.moph.go.th/das/journal_detail.php?publish=16336&deptcode=das (in Thai).

13. D'aes T, Van de Sande D, De Buck E, Zachee P, Compernolle V, Vandekerckhove P. Does cold storage of blood before transfusion prevent the transmission of syphilis? A systematic review and meta-analysis. Vox Sang. 2024;119:219-31.

14. AABB. Donor safety, sreening and testing [Internet]. Washington (DC): AABB [cited 2026 Sep 1]. Available from: https://www.aabb.org/regulatory-and-advocacy/regulatory-affairs/regulatory-for-blood/donor-safety-screening-and-testing.

15. Adegoke AO, Akanni OE. Survival of Treponema pallidum in banked blood for prevention of Syphilis transmission. N Am J Med Sci. 2011;3:329-32.

16. National Blood Centre, Thai Red Cross Society. Standards for blood banks and transfusion services. 6th ed. Bangkok: National Blood Centre, Thai Red Cross Society; 2026. (in Thai).

17. Sermsaksasithorn P, Wongkijpatana K. Deferral and complications from blood donation in educational institutions. J Hematol Transfus Med. 2026;36:147-51.

18. Pedrosa NL, Pinheiro PM, de Araújo WN. Acquired syphilis in the context of pre-exposure prophylaxis for HIV: a systematic review of the scientific literature. AIDS Rev. 2024;26:121-9.

Downloads

Published

2026-11-06

Issue

Section

บทความพิเศษ (Special article)