Apheresis : Advance in Transfusion Services in Blood Bank, Rajavithi Hospital
Keywords:
Apheresis, Leukapheresis, Single donor platelet (SDP), YieldAbstract
Abstract : Since November 1996, Blood Bank Rajavithi Hospital has provided "Apheresis services, using continuous low computerized system blood cell separator. Through December 1997, 35 apheresis procedures were done. One therapeutic leukapheresis was done in order to remove excessive white blood cells from an acute monoblastic leukemic patient, 34 donating platelet apheresis were performed to prepare single-donor-platelet (SDP) which 30 cases were successfully done, one was half proceeded and 3 were failed. Among 30 cases, the average yield of SDP was 4.0110:98x10"/bag. According to the American Association of Blood Banks (AABB), the yield of of one SDP unit should contain a minimum of 3x10" platelets in at least 75% of the units tested. In this report, 26 SDP (86.67%) were above the minimal required standard while 4 SDP (13.33%) were below The etficiency of the blood cell separator for platelet harvesting was about 479%. Pre-donation platelet level, the total volume of donors' blood processing through the machine and SDP collected volume were observed as the influencing factors on the outcoming yield. The study leads to the improvement of quality, efficiency and the implementation of apheresis services to the patients.
Downloads
References
Duke WW. The relationship of blood platelets to hemorrhagic disease. Description of a method for determining the bleeding time and report of three cases of hemorrhagic disease relieved by transfusion. JAMA 1910;55:1185-92.
Rosenfield CS, Bodensteiner DC. Detection of platelet alloantibodies by flow cytometry. Characterization and clinical significance. Am J Clin Pathol 1986;85:207-12.
Kahn R. Clinical evaluation of platelets in thrombo-cytopenic patients. Methods and interpretation. Vox Sang 1981;40:87-97.
Tosato G, Applebaum FR, Diesseroth AB. HLA-matched platelet transfusion therapy of severe aplastic anemia. Blood 1978;9:846-54.
Yankee RA, Graff KS, Dowling R, Handerson E.Selection of a related compatible platelet donors by lymphocyte HLA matched. N Eng J Med 1973,288:760-4.
Kickler TS, Ness PM, Braine HG. Platelet crossmatching. A direct approach to the selection of platelet. transfusions for the alloimmunized thrombocytopenic patient. Am J Clin Pathol 1988;90:69-72.
Kelly DL, et al. High-yield platelet concentrates attainable by continuous quality improvement reduce platelet transfusion cost and donor exposure. Transfusion 1997;37:482-6.
Klein HV. D4,000 Platelet ; platelets, pheresis. Standards for blood banks and transfusion services. 17th ed. Bethesda : Am Asso Blood Banks 1996:15.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
